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Activation of the cardiac mTOR/p70(S6K) pathway by leucine requires PDK1 and correlates with PRAS40 phosphorylation.
Sanchez Canedo C, Demeulder B, Ginion A, Bayascas JR, Balligand JL, Alessi DR, Vanoverschelde JL, Beauloye C, Hue L, Bertrand L. Sanchez Canedo C, et al. Among authors: beauloye c. Am J Physiol Endocrinol Metab. 2010 Apr;298(4):E761-9. doi: 10.1152/ajpendo.00421.2009. Epub 2010 Jan 5. Am J Physiol Endocrinol Metab. 2010. PMID: 20051528 Free article.
HMGCoA reductase inhibition reverses myocardial fibrosis and diastolic dysfunction through AMP-activated protein kinase activation in a mouse model of metabolic syndrome.
Hermida N, Markl A, Hamelet J, Van Assche T, Vanderper A, Herijgers P, van Bilsen M, Hilfiker-Kleiner D, Noppe G, Beauloye C, Horman S, Balligand JL. Hermida N, et al. Among authors: beauloye c. Cardiovasc Res. 2013 Jul 1;99(1):44-54. doi: 10.1093/cvr/cvt070. Epub 2013 Mar 29. Cardiovasc Res. 2013. PMID: 23542580
Enhanced expression of β3-adrenoceptors in cardiac myocytes attenuates neurohormone-induced hypertrophic remodeling through nitric oxide synthase.
Belge C, Hammond J, Dubois-Deruy E, Manoury B, Hamelet J, Beauloye C, Markl A, Pouleur AC, Bertrand L, Esfahani H, Jnaoui K, Götz KR, Nikolaev VO, Vanderper A, Herijgers P, Lobysheva I, Iaccarino G, Hilfiker-Kleiner D, Tavernier G, Langin D, Dessy C, Balligand JL. Belge C, et al. Among authors: beauloye c. Circulation. 2014 Jan 28;129(4):451-62. doi: 10.1161/CIRCULATIONAHA.113.004940. Epub 2013 Nov 4. Circulation. 2014. PMID: 24190960
The Ca(2+) /calmodulin-dependent kinase kinase β-AMP-activated protein kinase-α1 pathway regulates phosphorylation of cytoskeletal targets in thrombin-stimulated human platelets.
Onselaer MB, Oury C, Hunter RW, Eeckhoudt S, Barile N, Lecut C, Morel N, Viollet B, Jacquet LM, Bertrand L, Sakamoto K, Vanoverschelde JL, Beauloye C, Horman S. Onselaer MB, et al. Among authors: beauloye c. J Thromb Haemost. 2014 Jun;12(6):973-86. doi: 10.1111/jth.12568. J Thromb Haemost. 2014. PMID: 24655923 Free article.
A-769662 potentiates the effect of other AMP-activated protein kinase activators on cardiac glucose uptake.
Timmermans AD, Balteau M, Gélinas R, Renguet E, Ginion A, de Meester C, Sakamoto K, Balligand JL, Bontemps F, Vanoverschelde JL, Horman S, Beauloye C, Bertrand L. Timmermans AD, et al. Among authors: beauloye c. Am J Physiol Heart Circ Physiol. 2014 Jun 15;306(12):H1619-30. doi: 10.1152/ajpheart.00965.2013. Epub 2014 Apr 18. Am J Physiol Heart Circ Physiol. 2014. PMID: 24748590 Free article.
Reduced scar maturation and contractility lead to exaggerated left ventricular dilation after myocardial infarction in mice lacking AMPKα1.
Noppe G, Dufeys C, Buchlin P, Marquet N, Castanares-Zapatero D, Balteau M, Hermida N, Bouzin C, Esfahani H, Viollet B, Bertrand L, Balligand JL, Vanoverschelde JL, Beauloye C, Horman S. Noppe G, et al. Among authors: beauloye c. J Mol Cell Cardiol. 2014 Sep;74:32-43. doi: 10.1016/j.yjmcc.2014.04.018. Epub 2014 May 5. J Mol Cell Cardiol. 2014. PMID: 24805196
Loss of Mouse P2Y6 Nucleotide Receptor Is Associated with Physiological Macrocardia and Amplified Pathological Cardiac Hypertrophy.
Clouet S, Di Pietrantonio L, Daskalopoulos EP, Esfahani H, Horckmans M, Vanorlé M, Lemaire A, Balligand JL, Beauloye C, Boeynaems JM, Communi D. Clouet S, et al. Among authors: beauloye c. J Biol Chem. 2016 Jul 22;291(30):15841-52. doi: 10.1074/jbc.M115.684118. Epub 2016 May 26. J Biol Chem. 2016. PMID: 27231349 Free PMC article.
178 results