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New insights in the development of positive allosteric modulators of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors belonging to 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxides: Introduction of (mono/difluoro)methyl groups at the 2-position of the thiadiazine ring.
Eur J Med Chem. 2023 Mar 15;250:115221. doi: 10.1016/j.ejmech.2023.115221. Epub 2023 Feb 24.
Eur J Med Chem. 2023.
PMID: 36863228
Exploring thienothiadiazine dioxides as isosteric analogues of benzo- and pyridothiadiazine dioxides in the search of new AMPA and kainate receptor positive allosteric modulators.
Francotte P, Bay Y, Goffin E, Colson T, Lesenfants C, Dorosz J, Laulumaa S, Fraikin P, de Tullio P, Beaufour C, Botez I, Pickering DS, Frydenvang K, Danober L, Kristensen AS, Kastrup JS, Pirotte B.
Francotte P, et al. Among authors: beaufour c.
Eur J Med Chem. 2024 Jan 15;264:116036. doi: 10.1016/j.ejmech.2023.116036. Epub 2023 Dec 9.
Eur J Med Chem. 2024.
PMID: 38101041
Free article.
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Therapeutic efficacy in experimental polyarthritis of viral-driven enkephalin overproduction in sensory neurons.
Braz J, Beaufour C, Coutaux A, Epstein AL, Cesselin F, Hamon M, Pohl M.
Braz J, et al. Among authors: beaufour c.
J Neurosci. 2001 Oct 15;21(20):7881-8. doi: 10.1523/JNEUROSCI.21-20-07881.2001.
J Neurosci. 2001.
PMID: 11588161
Free PMC article.
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Extracellular dopamine in the rat prefrontal cortex during reward-, punishment- and novelty-associated behaviour. Effects of diazepam.
Beaufour CC, Le Bihan C, Hamon M, Thiébot M.
Beaufour CC, et al.
Pharmacol Biochem Behav. 2001 May-Jun;69(1-2):133-42. doi: 10.1016/s0091-3057(01)00492-0.
Pharmacol Biochem Behav. 2001.
PMID: 11420078
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Extracellular serotonin is enhanced in the striatum, but not in the dorsal hippocampus or prefrontal cortex, in rats subjected to an operant conflict procedure.
Beaufour CC, Le Bihan C, Hamon M, Thiébot MH.
Beaufour CC, et al.
Behav Neurosci. 2001 Feb;115(1):125-37. doi: 10.1037/0735-7044.115.1.125.
Behav Neurosci. 2001.
PMID: 11256436
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Altered expression and functions of serotonin 5-HT1A and 5-HT1B receptors in knock-out mice lacking the 5-HT transporter.
Fabre V, Beaufour C, Evrard A, Rioux A, Hanoun N, Lesch KP, Murphy DL, Lanfumey L, Hamon M, Martres MP.
Fabre V, et al. Among authors: beaufour c.
Eur J Neurosci. 2000 Jul;12(7):2299-310. doi: 10.1046/j.1460-9568.2000.00126.x.
Eur J Neurosci. 2000.
PMID: 10947809
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Effects of chronic antidepressants in an operant conflict procedure of anxiety in the rat.
Beaufour CC, Ballon N, Le Bihan C, Hamon M, Thiébot MH.
Beaufour CC, et al.
Pharmacol Biochem Behav. 1999 Apr;62(4):591-9. doi: 10.1016/s0091-3057(98)00180-4.
Pharmacol Biochem Behav. 1999.
PMID: 10208363
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