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Repurposing disulfiram, an alcohol-abuse drug, in neuroblastoma causes KAT2A downregulation and in vivo activity with a water/oil emulsion.
Beaudry A, Jacques-Ricard S, Darracq A, Sgarioto N, Garcia A, García TR, Lemieux W, Béland K, Haddad E, Cordeiro P, Duval M, McGraw S, Richer C, Caron M, Marois F, St-Onge P, Sinnett D, Banquy X, Raynal NJ. Beaudry A, et al. Sci Rep. 2023 Sep 30;13(1):16443. doi: 10.1038/s41598-023-43219-2. Sci Rep. 2023. PMID: 37777587 Free PMC article.
Heart failure drug proscillaridin A targets MYC overexpressing leukemia through global loss of lysine acetylation.
Da Costa EM, Armaos G, McInnes G, Beaudry A, Moquin-Beaudry G, Bertrand-Lehouillier V, Caron M, Richer C, St-Onge P, Johnson JR, Krogan N, Sai Y, Downey M, Rafei M, Boileau M, Eppert K, Flores-Díaz E, Haman A, Hoang T, Sinnett D, Beauséjour C, McGraw S, Raynal NJ. Da Costa EM, et al. Among authors: beaudry a. J Exp Clin Cancer Res. 2019 Jun 13;38(1):251. doi: 10.1186/s13046-019-1242-8. J Exp Clin Cancer Res. 2019. PMID: 31196146 Free PMC article.
DNA Methylation-Targeted Drugs.
Da Costa EM, McInnes G, Beaudry A, Raynal NJ. Da Costa EM, et al. Among authors: beaudry a. Cancer J. 2017 Sep/Oct;23(5):270-276. doi: 10.1097/PPO.0000000000000278. Cancer J. 2017. PMID: 28926427 Review.
Targeting Calcium Signaling Induces Epigenetic Reactivation of Tumor Suppressor Genes in Cancer.
Raynal NJ, Lee JT, Wang Y, Beaudry A, Madireddi P, Garriga J, Malouf GG, Dumont S, Dettman EJ, Gharibyan V, Ahmed S, Chung W, Childers WE, Abou-Gharbia M, Henry RA, Andrews AJ, Jelinek J, Cui Y, Baylin SB, Gill DL, Issa JP. Raynal NJ, et al. Among authors: beaudry a. Cancer Res. 2016 Mar 15;76(6):1494-505. doi: 10.1158/0008-5472.CAN-14-2391. Epub 2015 Dec 30. Cancer Res. 2016. PMID: 26719529 Free PMC article.
TACIMA-218: A Novel Pro-Oxidant Agent Exhibiting Selective Antitumoral Activity.
Abusarah J, Cui Y, El-Hachem N, El-Kadiry AE, Hammond-Martel I, Wurtele H, Beaudry A, Raynal NJ, Robert F, Pelletier J, Jankovic M, Mercier F, Kamyabiazar S, Annabi B, Rafei M. Abusarah J, et al. Among authors: beaudry a. Mol Cancer Ther. 2021 Jan;20(1):37-49. doi: 10.1158/1535-7163.MCT-20-0333. Epub 2020 Oct 21. Mol Cancer Ther. 2021. PMID: 33087510
Comparison of the "Tall and Fall" Versus "Drop and Drive" Pitching Styles: Analysis of Major League Baseball Pitchers During a Single Season.
Beaudry MF, Beaudry AG, Bradley JP, Haynes DE, Holland G, Edwards A, Baker BA, Jacobson BR, Chetlin RD. Beaudry MF, et al. Among authors: beaudry ag. Orthop J Sports Med. 2023 May 22;11(5):23259671231173691. doi: 10.1177/23259671231173691. eCollection 2023 May. Orthop J Sports Med. 2023. PMID: 37250742 Free PMC article.
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