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Sofalcone upregulates the nuclear factor (erythroid-derived 2)-like 2/heme oxygenase-1 pathway, reduces soluble fms-like tyrosine kinase-1, and quenches endothelial dysfunction: potential therapeutic for preeclampsia.
Onda K, Tong S, Nakahara A, Kondo M, Monchusho H, Hirano T, Kaitu'u-Lino T, Beard S, Binder N, Tuohey L, Brownfoot F, Hannan NJ. Onda K, et al. Among authors: beard s. Hypertension. 2015 Apr;65(4):855-62. doi: 10.1161/HYPERTENSIONAHA.114.04781. Epub 2015 Feb 9. Hypertension. 2015. PMID: 25667213
Heme Oxygenase-1 Is Not Decreased in Preeclamptic Placenta and Does Not Negatively Regulate Placental Soluble fms-Like Tyrosine Kinase-1 or Soluble Endoglin Secretion.
Tong S, Kaitu'u-Lino TJ, Onda K, Beard S, Hastie R, Binder NK, Cluver C, Tuohey L, Whitehead C, Brownfoot F, De Silva M, Hannan NJ. Tong S, et al. Among authors: beard s. Hypertension. 2015 Nov;66(5):1073-81. doi: 10.1161/HYPERTENSIONAHA.115.05847. Epub 2015 Aug 31. Hypertension. 2015. PMID: 26324507
Proton Pump Inhibitors Decrease Soluble fms-Like Tyrosine Kinase-1 and Soluble Endoglin Secretion, Decrease Hypertension, and Rescue Endothelial Dysfunction.
Onda K, Tong S, Beard S, Binder N, Muto M, Senadheera SN, Parry L, Dilworth M, Renshall L, Brownfoot F, Hastie R, Tuohey L, Palmer K, Hirano T, Ikawa M, Kaitu'u-Lino T, Hannan NJ. Onda K, et al. Among authors: beard s. Hypertension. 2017 Mar;69(3):457-468. doi: 10.1161/HYPERTENSIONAHA.116.08408. Epub 2017 Jan 23. Hypertension. 2017. PMID: 28115513
209 results