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Biallelic DAW1 variants cause a motile ciliopathy characterized by laterality defects and subtle ciliary beating abnormalities.
Leslie JS, Hjeij R, Vivante A, Bearce EA, Dyer L, Wang J, Rawlins L, Kennedy J, Ubeyratna N, Fasham J, Irons ZH, Craig SB, Koenig J, George S, Pode-Shakked B, Bolkier Y, Barel O, Mane S, Frederiksen KK, Wenger O, Scott E, Cross HE, Lorentzen E, Norris DP, Anikster Y, Omran H, Grimes DT, Crosby AH, Baple EL. Leslie JS, et al. Among authors: bearce ea. Genet Med. 2022 Nov;24(11):2249-2261. doi: 10.1016/j.gim.2022.07.019. Epub 2022 Sep 8. Genet Med. 2022. PMID: 36074124 Free PMC article.
Daw1 regulates the timely onset of cilia motility during development.
Bearce EA, Irons ZH, Craig SB, Kuhns CJ, Sabazali C, Farnsworth DR, Miller AC, Grimes DT. Bearce EA, et al. Development. 2022 Jun 15;149(12):dev200017. doi: 10.1242/dev.200017. Epub 2022 Jun 16. Development. 2022. PMID: 35708608 Free PMC article.
TACC3 is a microtubule plus end-tracking protein that promotes axon elongation and also regulates microtubule plus end dynamics in multiple embryonic cell types.
Nwagbara BU, Faris AE, Bearce EA, Erdogan B, Ebbert PT, Evans MF, Rutherford EL, Enzenbacher TB, Lowery LA. Nwagbara BU, et al. Among authors: bearce ea. Mol Biol Cell. 2014 Nov 1;25(21):3350-62. doi: 10.1091/mbc.E14-06-1121. Epub 2014 Sep 3. Mol Biol Cell. 2014. PMID: 25187649 Free PMC article.
Variation in traction forces during cell cycle progression.
Vianay B, Senger F, Alamos S, Anjur-Dietrich M, Bearce E, Cheeseman B, Lee L, Théry M. Vianay B, et al. Biol Cell. 2018 Apr;110(4):91-96. doi: 10.1111/boc.201800006. Epub 2018 Mar 12. Biol Cell. 2018. PMID: 29388708
12 results