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Page 1
Time-resolved crystallography captures light-driven DNA repair.
Christou NE, Apostolopoulou V, Melo DVM, Ruppert M, Fadini A, Henkel A, Sprenger J, Oberthuer D, Günther S, Pateras A, Rahmani Mashhour A, Yefanov OM, Galchenkova M, Reinke PYA, Kremling V, Scheer TES, Lange ER, Middendorf P, Schubert R, De Zitter E, Lumbao-Conradson K, Herrmann J, Rahighi S, Kunavar A, Beale EV, Beale JH, Cirelli C, Johnson PJM, Dworkowski F, Ozerov D, Bertrand Q, Wranik M, Bacellar C, Bajt S, Wakatsuki S, Sellberg JA, Huse N, Turk D, Chapman HN, Lane TJ. Christou NE, et al. Among authors: beale jh. Science. 2023 Dec;382(6674):1015-1020. doi: 10.1126/science.adj4270. Epub 2023 Nov 30. Science. 2023. PMID: 38033070
Successful sample preparation for serial crystallography experiments.
Beale JH, Bolton R, Marshall SA, Beale EV, Carr SB, Ebrahim A, Moreno-Chicano T, Hough MA, Worrall JAR, Tews I, Owen RL. Beale JH, et al. Among authors: beale ev. J Appl Crystallogr. 2019 Nov 14;52(Pt 6):1385-1396. doi: 10.1107/S1600576719013517. eCollection 2019 Dec 1. J Appl Crystallogr. 2019. PMID: 31798361 Free PMC article.
Versatile microporous polymer-based supports for serial macromolecular crystallography.
Martiel I, Beale JH, Karpik A, Huang CY, Vera L, Olieric N, Wranik M, Tsai CJ, Mühle J, Aurelius O, John J, Högbom M, Wang M, Marsh M, Padeste C. Martiel I, et al. Among authors: beale jh. Acta Crystallogr D Struct Biol. 2021 Sep 1;77(Pt 9):1153-1167. doi: 10.1107/S2059798321007324. Epub 2021 Aug 23. Acta Crystallogr D Struct Biol. 2021. PMID: 34473086 Free PMC article.
Watching the release of a photopharmacological drug from tubulin using time-resolved serial crystallography.
Wranik M, Weinert T, Slavov C, Masini T, Furrer A, Gaillard N, Gioia D, Ferrarotti M, James D, Glover H, Carrillo M, Kekilli D, Stipp R, Skopintsev P, Brünle S, Mühlethaler T, Beale J, Gashi D, Nass K, Ozerov D, Johnson PJM, Cirelli C, Bacellar C, Braun M, Wang M, Dworkowski F, Milne C, Cavalli A, Wachtveitl J, Steinmetz MO, Standfuss J. Wranik M, et al. Nat Commun. 2023 Feb 17;14(1):903. doi: 10.1038/s41467-023-36481-5. Nat Commun. 2023. PMID: 36807348 Free PMC article.
A multi-reservoir extruder for time-resolved serial protein crystallography and compound screening at X-ray free-electron lasers.
Wranik M, Kepa MW, Beale EV, James D, Bertrand Q, Weinert T, Furrer A, Glover H, Gashi D, Carrillo M, Kondo Y, Stipp RT, Khusainov G, Nass K, Ozerov D, Cirelli C, Johnson PJM, Dworkowski F, Beale JH, Stubbs S, Zamofing T, Schneider M, Krauskopf K, Gao L, Thorn-Seshold O, Bostedt C, Bacellar C, Steinmetz MO, Milne C, Standfuss J. Wranik M, et al. Among authors: beale jh. Nat Commun. 2023 Dec 2;14(1):7956. doi: 10.1038/s41467-023-43523-5. Nat Commun. 2023. PMID: 38042952 Free PMC article.
An on-demand, drop-on-drop method for studying enzyme catalysis by serial crystallography.
Butryn A, Simon PS, Aller P, Hinchliffe P, Massad RN, Leen G, Tooke CL, Bogacz I, Kim IS, Bhowmick A, Brewster AS, Devenish NE, Brem J, Kamps JJAG, Lang PA, Rabe P, Axford D, Beale JH, Davy B, Ebrahim A, Orlans J, Storm SLS, Zhou T, Owada S, Tanaka R, Tono K, Evans G, Owen RL, Houle FA, Sauter NK, Schofield CJ, Spencer J, Yachandra VK, Yano J, Kern JF, Orville AM. Butryn A, et al. Among authors: beale jh. Nat Commun. 2021 Jul 22;12(1):4461. doi: 10.1038/s41467-021-24757-7. Nat Commun. 2021. PMID: 34294694 Free PMC article.
Probing ligand binding of endothiapepsin by `temperature-resolved' macromolecular crystallography.
Huang CY, Aumonier S, Engilberge S, Eris D, Smith KML, Leonarski F, Wojdyla JA, Beale JH, Buntschu D, Pauluhn A, Sharpe ME, Metz A, Olieric V, Wang M. Huang CY, et al. Among authors: beale jh. Acta Crystallogr D Struct Biol. 2022 Aug 1;78(Pt 8):964-974. doi: 10.1107/S205979832200612X. Epub 2022 Jul 27. Acta Crystallogr D Struct Biol. 2022. PMID: 35916221 Free PMC article.
A standard descriptor for fixed-target serial crystallography.
Owen RL, de Sanctis D, Pearson AR, Beale JH. Owen RL, et al. Among authors: beale jh. Acta Crystallogr D Struct Biol. 2023 Aug 1;79(Pt 8):668-672. doi: 10.1107/S2059798323005429. Epub 2023 Jul 18. Acta Crystallogr D Struct Biol. 2023. PMID: 37463110 Free PMC article.
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