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Watching the release of a photopharmacological drug from tubulin using time-resolved serial crystallography.
Wranik M, Weinert T, Slavov C, Masini T, Furrer A, Gaillard N, Gioia D, Ferrarotti M, James D, Glover H, Carrillo M, Kekilli D, Stipp R, Skopintsev P, Brünle S, Mühlethaler T, Beale J, Gashi D, Nass K, Ozerov D, Johnson PJM, Cirelli C, Bacellar C, Braun M, Wang M, Dworkowski F, Milne C, Cavalli A, Wachtveitl J, Steinmetz MO, Standfuss J. Wranik M, et al. Among authors: beale j. Nat Commun. 2023 Feb 17;14(1):903. doi: 10.1038/s41467-023-36481-5. Nat Commun. 2023. PMID: 36807348 Free PMC article.
How best to use photons.
Winter G, Gildea RJ, Paterson NG, Beale J, Gerstel M, Axford D, Vollmar M, McAuley KE, Owen RL, Flaig R, Ashton AW, Hall DR. Winter G, et al. Among authors: beale j. Acta Crystallogr D Struct Biol. 2019 Mar 1;75(Pt 3):242-261. doi: 10.1107/S2059798319003528. Epub 2019 Mar 19. Acta Crystallogr D Struct Biol. 2019. PMID: 30950396 Free PMC article.
An on-demand, drop-on-drop method for studying enzyme catalysis by serial crystallography.
Butryn A, Simon PS, Aller P, Hinchliffe P, Massad RN, Leen G, Tooke CL, Bogacz I, Kim IS, Bhowmick A, Brewster AS, Devenish NE, Brem J, Kamps JJAG, Lang PA, Rabe P, Axford D, Beale JH, Davy B, Ebrahim A, Orlans J, Storm SLS, Zhou T, Owada S, Tanaka R, Tono K, Evans G, Owen RL, Houle FA, Sauter NK, Schofield CJ, Spencer J, Yachandra VK, Yano J, Kern JF, Orville AM. Butryn A, et al. Among authors: beale jh. Nat Commun. 2021 Jul 22;12(1):4461. doi: 10.1038/s41467-021-24757-7. Nat Commun. 2021. PMID: 34294694 Free PMC article.
Versatile microporous polymer-based supports for serial macromolecular crystallography.
Martiel I, Beale JH, Karpik A, Huang CY, Vera L, Olieric N, Wranik M, Tsai CJ, Mühle J, Aurelius O, John J, Högbom M, Wang M, Marsh M, Padeste C. Martiel I, et al. Among authors: beale jh. Acta Crystallogr D Struct Biol. 2021 Sep 1;77(Pt 9):1153-1167. doi: 10.1107/S2059798321007324. Epub 2021 Aug 23. Acta Crystallogr D Struct Biol. 2021. PMID: 34473086 Free PMC article.
120 results