Beaino W - Search Results

1

Identification of new molecular targets for PET imaging of the microglial anti-inflammatory activation state.

Villa A, Klein B, Janssen B, Pedragosa J, Pepe G, Zinnhardt B, Vugts DJ, Gelosa P, Sironi L, Beaino W, Damont A, Dollé F, Jego B, Winkeler A, Ory D, Solin O, Vercouillie J, Funke U, Laner-Plamberger S, Blomster LV, Christophersen P, Vegeto E, Aigner L, Jacobs A, Planas AM, Maggi A, Windhorst AD. Villa A, et al. Among authors: beaino w. Theranostics. 2018 Oct 27;8(19):5400-5418. doi: 10.7150/thno.25572. eCollection 2018. Theranostics. 2018. PMID: 30555554 Free PMC article.

2

Purinergic receptors P2Y12R and P2X7R: potential targets for PET imaging of microglia phenotypes in multiple sclerosis.

Beaino W, Janssen B, Kooij G, van der Pol SMA, van Het Hof B, van Horssen J, Windhorst AD, de Vries HE. Beaino W, et al. J Neuroinflammation. 2017 Dec 22;14(1):259. doi: 10.1186/s12974-017-1034-z. J Neuroinflammation. 2017. PMID: 29273052 Free PMC article.

3

Identification of the allosteric P2X₇ receptor antagonist [¹¹C]SMW139 as a PET tracer of microglial activation.

Janssen B, Vugts DJ, Wilkinson SM, Ory D, Chalon S, Hoozemans JJM, Schuit RC, Beaino W, Kooijman EJM, van den Hoek J, Chishty M, Doméné A, Van der Perren A, Villa A, Maggi A, Molenaar GT, Funke U, Shevchenko RV, Baekelandt V, Bormans G, Lammertsma AA, Kassiou M, Windhorst AD. Janssen B, et al. Among authors: beaino w. Sci Rep. 2018 Apr 26;8(1):6580. doi: 10.1038/s41598-018-24814-0. Sci Rep. 2018. PMID: 29700413 Free PMC article.

4

In vivo evaluation of two tissue transglutaminase PET tracers in an orthotopic tumour xenograft model.

van der Wildt B, Wilhelmus MMM, Beaino W, Kooijman EJM, Schuit RC, Bol JGJM, Breve JJP, Pasternack R, Lammertsma AA, Windhorst AD, Drukarch B. van der Wildt B, et al. Among authors: beaino w. EJNMMI Res. 2018 May 25;8(1):39. doi: 10.1186/s13550-018-0388-2. EJNMMI Res. 2018. PMID: 29802556 Free PMC article.

5

Synthesis and Preclinical Evaluation of the First Carbon-11 Labeled PET Tracers Targeting Substance P_1-7.

Pekošak A, Bulc JŽ, Korat Š, Schuit RC, Kooijman E, Vos R, Rongen M, Verlaan M, Takkenkamp K, Beaino W, Poot AJ, Windhorst AD. Pekošak A, et al. Among authors: beaino w. Mol Pharm. 2018 Nov 5;15(11):4872-4883. doi: 10.1021/acs.molpharmaceut.8b00518. Epub 2018 Oct 25. Mol Pharm. 2018. PMID: 30335399 Free PMC article.

6

The P2X₇ receptor tracer [¹¹C]SMW139 as an in vivo marker of neuroinflammation in multiple sclerosis: a first-in man study.

Hagens MHJ, Golla SSV, Janssen B, Vugts DJ, Beaino W, Windhorst AD, O'Brien-Brown J, Kassiou M, Schuit RC, Schwarte LA, de Vries HE, Killestein J, Barkhof F, van Berckel BNM, Lammertsma AA. Hagens MHJ, et al. Among authors: beaino w. Eur J Nucl Med Mol Imaging. 2020 Feb;47(2):379-389. doi: 10.1007/s00259-019-04550-x. Epub 2019 Nov 8. Eur J Nucl Med Mol Imaging. 2020. PMID: 31705174 Free PMC article.

7

Head-to-head comparison of DFO* and DFO chelators: selection of the best candidate for clinical ⁸⁹Zr-immuno-PET.

Chomet M, Schreurs M, Bolijn MJ, Verlaan M, Beaino W, Brown K, Poot AJ, Windhorst AD, Gill H, Marik J, Williams S, Cowell J, Gasser G, Mindt TL, van Dongen GAMS, Vugts DJ. Chomet M, et al. Among authors: beaino w. Eur J Nucl Med Mol Imaging. 2021 Mar;48(3):694-707. doi: 10.1007/s00259-020-05002-7. Epub 2020 Sep 5. Eur J Nucl Med Mol Imaging. 2021. PMID: 32889615 Free PMC article.

8

PET imaging of P2X₇R in the experimental autoimmune encephalomyelitis model of multiple sclerosis using [¹¹C]SMW139.

Beaino W, Janssen B, Kooijman E, Vos R, Schuit RC, O'Brien-Brown J, Kassiou M, van Het Hof B, Vugts DJ, de Vries HE, Windhorst AD. Beaino W, et al. J Neuroinflammation. 2020 Oct 14;17(1):300. doi: 10.1186/s12974-020-01962-7. J Neuroinflammation. 2020. PMID: 33054803 Free PMC article.

9

The Role of ⁸⁹Zr-Immuno-PET in Navigating and Derisking the Development of Biopharmaceuticals.

van Dongen GAMS, Beaino W, Windhorst AD, Zwezerijnen GJC, Oprea-Lager DE, Hendrikse NH, van Kuijk C, Boellaard R, Huisman MC, Vugts DJ. van Dongen GAMS, et al. Among authors: beaino w. J Nucl Med. 2021 Apr;62(4):438-445. doi: 10.2967/jnumed.119.239558. Epub 2020 Dec 4. J Nucl Med. 2021. PMID: 33277395 Free article. Review.

10

Performance of nanoScan PET/CT and PET/MR for quantitative imaging of ¹⁸F and ⁸⁹Zr as compared with ex vivo biodistribution in tumor-bearing mice.

Chomet M, Schreurs M, Vos R, Verlaan M, Kooijman EJ, Poot AJ, Boellaard R, Windhorst AD, van Dongen GA, Vugts DJ, Huisman MC, Beaino W. Chomet M, et al. Among authors: beaino w. EJNMMI Res. 2021 Jun 12;11(1):57. doi: 10.1186/s13550-021-00799-2. EJNMMI Res. 2021. PMID: 34117946 Free PMC article.

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