Bayrakdarian M - Search Results

1

Asymmetric Synthesis of a Potent CXCR7 Modulator Featuring a Hindered Tertiary β-Amino Amide Stereocenter.

Canterbury DP, Godin F, Desjardins S, Bayrakdarian M, Albert JS, Perry DA, Hesp KD. Canterbury DP, et al. Among authors: bayrakdarian m. Org Lett. 2018 Sep 7;20(17):5336-5339. doi: 10.1021/acs.orglett.8b02261. Epub 2018 Aug 17. Org Lett. 2018. PMID: 30118238

2

Discovery of P2X3 selective antagonists for the treatment of chronic pain.

Cantin LD, Bayrakdarian M, Buon C, Grazzini E, Hu YJ, Labrecque J, Leung C, Luo X, Martino G, Paré M, Payza K, Popovic N, Projean D, Santhakumar V, Walpole C, Yu XH, Tomaszewski MJ. Cantin LD, et al. Among authors: bayrakdarian m. Bioorg Med Chem Lett. 2012 Apr 1;22(7):2565-71. doi: 10.1016/j.bmcl.2012.01.124. Epub 2012 Feb 9. Bioorg Med Chem Lett. 2012. PMID: 22370269

3

Development of 2,4-diaminopyrimidine derivatives as novel SNSR4 antagonists.

Bayrakdarian M, Butterworth J, Hu YJ, Santhakumar V, Tomaszewski MJ. Bayrakdarian M, et al. Bioorg Med Chem Lett. 2011 Apr 1;21(7):2102-5. doi: 10.1016/j.bmcl.2011.01.138. Epub 2011 Feb 3. Bioorg Med Chem Lett. 2011. PMID: 21333534

4

Discovery and pharmacological characterization of a small-molecule antagonist at neuromedin U receptor NMUR2.

Liu JJ, Payza K, Huang J, Liu R, Chen T, Coupal M, Laird JM, Cao CQ, Butterworth J, Lapointe S, Bayrakdarian M, Trivedi S, Bostwick JR. Liu JJ, et al. Among authors: bayrakdarian m. J Pharmacol Exp Ther. 2009 Jul;330(1):268-75. doi: 10.1124/jpet.109.152967. Epub 2009 Apr 15. J Pharmacol Exp Ther. 2009. PMID: 19369576

5

Total synthesis of A-315675: a potent inhibitor of influenza neuraminidase.

Hanessian S, Bayrakdarian M, Luo X. Hanessian S, et al. Among authors: bayrakdarian m. J Am Chem Soc. 2002 May 1;124(17):4716-21. doi: 10.1021/ja0126226. J Am Chem Soc. 2002. PMID: 11971721

6

Phenolic P2/P3 core motif as thrombin inhibitors--design, synthesis, and X-ray co-crystal structure.

Hanessian S, Therrien E, van Otterlo WA, Bayrakdarian M, Nilsson I, Fjellström O, Xue Y. Hanessian S, et al. Among authors: bayrakdarian m. Bioorg Med Chem Lett. 2006 Feb 15;16(4):1032-6. doi: 10.1016/j.bmcl.2005.10.082. Epub 2005 Nov 15. Bioorg Med Chem Lett. 2006. PMID: 16290930

7

Design, synthesis, and thrombin-inhibitory activity of pyridin-2-ones as P2/P3 core motifs.

Hanessian S, Simard D, Bayrakdarian M, Therrien E, Nilsson I, Fjellström O. Hanessian S, et al. Among authors: bayrakdarian m. Bioorg Med Chem Lett. 2008 Mar 15;18(6):1972-6. doi: 10.1016/j.bmcl.2008.01.122. Epub 2008 Feb 7. Bioorg Med Chem Lett. 2008. PMID: 18289852

8

Pyrrolidine as a cogwheel-like scaffold for the deployment of diverse functionality through cycloaddition reactions of metallo-1,3-dipoles in aqueous media.

Hanessian S, Bayrakdarian M. Hanessian S, et al. Among authors: bayrakdarian m. Bioorg Med Chem Lett. 2000 Mar 6;10(5):427-31. doi: 10.1016/s0960-894x(00)00020-2. Bioorg Med Chem Lett. 2000. PMID: 10743941

9

Structure-based design, synthesis, and memapsin 2 (BACE) inhibitory activity of carbocyclic and heterocyclic peptidomimetics.

Hanessian S, Yun H, Hou Y, Yang G, Bayrakdarian M, Therrien E, Moitessier N, Roggo S, Veenstra S, Tintelnot-Blomley M, Rondeau JM, Ostermeier C, Strauss A, Ramage P, Paganetti P, Neumann U, Betschart C. Hanessian S, et al. Among authors: bayrakdarian m. J Med Chem. 2005 Aug 11;48(16):5175-90. doi: 10.1021/jm050142+. J Med Chem. 2005. PMID: 16078837

10

Design and synthesis of a novel class of constrained tricyclic pyrrolizidinone carboxylic acids as carbapenem mimics.

Hanessian S, Buckle R, Bayrakdarian M. Hanessian S, et al. Among authors: bayrakdarian m. J Org Chem. 2002 May 17;67(10):3387-97. doi: 10.1021/jo0111715. J Org Chem. 2002. PMID: 12003550

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