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A variant in the MICA gene is associated with liver fibrosis progression in chronic hepatitis C through TGF-β1 dependent mechanisms.
Sharkawy RE, Bayoumi A, Metwally M, Mangia A, Berg T, Romero-Gomez M, Abate ML, Irving WL, Sheridan D, Dore GJ, Spengler U, Lampertico P, Bugianesi E, Weltman M, Mollison L, Cheng W, Riordan S, Santoro R, Gallego-Durán R, Fischer J, Nattermann J, D'Ambrosio R, McLeod D, Powell E, Latchoumanin O, Thabet K, Najim MAM, Douglas MW, Liddle C, Qiao L, George J, Eslam M; International Liver Disease Genetics Consortium (ILDGC). Sharkawy RE, et al. Among authors: bayoumi a. Sci Rep. 2019 Feb 5;9(1):1439. doi: 10.1038/s41598-018-35736-2. Sci Rep. 2019. PMID: 30723271 Free PMC article.
A STAT4 variant increases liver fibrosis risk in Caucasian patients with chronic hepatitis B.
El Sharkawy R, Thabet K, Lampertico P, Petta S, Mangia A, Berg T, Metwally M, Bayoumi A, Boonstra A, Brouwer WP, Smedile A, Abate ML, Loglio A, Douglas MW, Khan A, Santoro R, Fischer J, Leeming DJ, Liddle C, George J, Eslam M. El Sharkawy R, et al. Among authors: bayoumi a. Aliment Pharmacol Ther. 2018 Sep;48(5):564-573. doi: 10.1111/apt.14866. Epub 2018 Jul 2. Aliment Pharmacol Ther. 2018. PMID: 29963713 Free article.
A polymorphism in the Irisin-encoding gene (FNDC5) associates with hepatic steatosis by differential miRNA binding to the 3'UTR.
Metwally M, Bayoumi A, Romero-Gomez M, Thabet K, John M, Adams LA, Huo X, Aller R, García-Monzón C, Teresa Arias-Loste M, Bugianesi E, Miele L, Gallego-Durán R, Fischer J, Berg T, Liddle C, Qiao L, George J, Eslam M. Metwally M, et al. Among authors: bayoumi a. J Hepatol. 2019 Mar;70(3):494-500. doi: 10.1016/j.jhep.2018.10.021. Epub 2018 Oct 31. J Hepatol. 2019. PMID: 30389552 Free article.
Lean NAFLD: A Distinct Entity Shaped by Differential Metabolic Adaptation.
Chen F, Esmaili S, Rogers GB, Bugianesi E, Petta S, Marchesini G, Bayoumi A, Metwally M, Azardaryany MK, Coulter S, Choo JM, Younes R, Rosso C, Liddle C, Adams LA, Craxì A, George J, Eslam M. Chen F, et al. Among authors: bayoumi a. Hepatology. 2020 Apr;71(4):1213-1227. doi: 10.1002/hep.30908. Epub 2020 Jan 24. Hepatology. 2020. PMID: 31442319 Free article.
IFNL3 genotype is associated with pulmonary fibrosis in patients with systemic sclerosis.
Metwally M, Thabet K, Bayoumi A, Nikpour M, Stevens W, Sahhar J, Zochling J, Roddy J, Tymms K, Strickland G, Lester S, Rischmueller M, Ngian GS, Walker J, Hissaria P, Shaker O, Liddle C, Manolios N, Beretta L, Proudman S, George J, Eslam M. Metwally M, et al. Among authors: bayoumi a. Sci Rep. 2019 Oct 16;9(1):14834. doi: 10.1038/s41598-019-50709-9. Sci Rep. 2019. PMID: 31619697 Free PMC article.
Genetic variation in the TLL1 gene is not associated with fibrosis in patients with metabolic associated fatty liver disease.
Bayoumi A, Jalil I, Metwally M, Adams LA, Aller R, García-Monzón C, Arias-Loste MT, Miele L, Petta S, Craxì A, Gallego-Durán R, Fischer J, Berg T, Qiao L, Liddle C, Bugianesi E, Romero-Gomez M, George J, Eslam M. Bayoumi A, et al. PLoS One. 2020 Dec 11;15(12):e0243590. doi: 10.1371/journal.pone.0243590. eCollection 2020. PLoS One. 2020. PMID: 33306709 Free PMC article.
Mistranslation Drives Alterations in Protein Levels and the Effects of a Synonymous Variant at the Fibroblast Growth Factor 21 Locus.
Bayoumi A, Elsayed A, Han S, Petta S, Adams LA, Aller R, Khan A, García-Monzón C, Arias-Loste MT, Miele L, Latchoumanin O, Alenizi S, Gallego-Durán R, Fischer J, Berg T, Craxì A, Metwally M, Qiao L, Liddle C, Yki-Järvinen H, Bugianesi E, Romero-Gomez M, George J, Eslam M. Bayoumi A, et al. Adv Sci (Weinh). 2021 May 1;8(11):2004168. doi: 10.1002/advs.202004168. eCollection 2021 Jun. Adv Sci (Weinh). 2021. PMID: 34141520 Free PMC article.
Copy number variation and expression of exportin-4 associates with severity of fibrosis in metabolic associated fatty liver disease.
Metwally M, Bayoumi A, Khan A, Adams LA, Aller R, García-Monzón C, Arias-Loste MT, Bugianesi E, Miele L, Anna A, Latchoumanin O, Han S, Alenizi S, Sharkawy RE, Elattar A, Gallego-Durán R, Fischer J, Berg T, Liddle C, Romero-Gomez M, George J, Eslam M. Metwally M, et al. Among authors: bayoumi a. EBioMedicine. 2021 Aug;70:103521. doi: 10.1016/j.ebiom.2021.103521. Epub 2021 Aug 11. EBioMedicine. 2021. PMID: 34388518 Free PMC article.
446 results