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A synbiotic concept containing spore-forming Bacillus strains and a prebiotic fiber blend consistently enhanced metabolic activity by modulation of the gut microbiome in vitro.
Int J Pharm X. 2019 Jul 6;1:100021. doi: 10.1016/j.ijpx.2019.100021. eCollection 2019 Dec.
Int J Pharm X. 2019.
PMID: 31517286
Free PMC article.
Treatment with a spore-based probiotic containing five strains of Bacillus induced changes in the metabolic activity and community composition of the gut microbiota in a SHIME® model of the human gastrointestinal system.
Marzorati M, Van den Abbeele P, Bubeck S, Bayne T, Krishnan K, Young A.
Marzorati M, et al.
Food Res Int. 2021 Nov;149:110676. doi: 10.1016/j.foodres.2021.110676. Epub 2021 Aug 30.
Food Res Int. 2021.
PMID: 34600678
Free article.
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Bacillus subtilis HU58 and Bacillus coagulans SC208 Probiotics Reduced the Effects of Antibiotic-Induced Gut Microbiome Dysbiosis in An M-SHIME® Model.
Marzorati M, Abbeele PVD, Bubeck SS, Bayne T, Krishnan K, Young A, Mehta D, DeSouza A.
Marzorati M, et al.
Microorganisms. 2020 Jul 11;8(7):1028. doi: 10.3390/microorganisms8071028.
Microorganisms. 2020.
PMID: 32664604
Free PMC article.
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Effects of combined prebiotic, probiotic, IgG and amino acid supplementation on the gut microbiome of patients with inflammatory bowel disease.
Marzorati M, Bubeck S, Bayne T, Krishnan K, Giusto M.
Marzorati M, et al.
Future Microbiol. 2022 Nov;17:1307-1324. doi: 10.2217/fmb-2022-0066. Epub 2022 Sep 16.
Future Microbiol. 2022.
PMID: 36111808
Free article.
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An Oral Formulation of the Probiotic, Bacillus subtilis HU58, Was Safe and Well Tolerated in a Pilot Study of Patients with Hepatic Encephalopathy.
Yossef S, Clark F, Bubeck SS, Abernethy J, Bayne T, Krishnan K, Young A.
Yossef S, et al.
Evid Based Complement Alternat Med. 2020 Jun 30;2020:1463108. doi: 10.1155/2020/1463108. eCollection 2020.
Evid Based Complement Alternat Med. 2020.
PMID: 32714397
Free PMC article.
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