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DNA Damage: A Main Determinant of Vascular Aging.
Bautista-Niño PK, Portilla-Fernandez E, Vaughan DE, Danser AH, Roks AJ. Bautista-Niño PK, et al. Int J Mol Sci. 2016 May 18;17(5):748. doi: 10.3390/ijms17050748. Int J Mol Sci. 2016. PMID: 27213333 Free PMC article. Review.
Dietary restriction but not angiotensin II type 1 receptor blockade improves DNA damage-related vasodilator dysfunction in rapidly aging Ercc1Δ/- mice.
Wu H, van Thiel BS, Bautista-Niño PK, Reiling E, Durik M, Leijten FPJ, Ridwan Y, Brandt RMC, van Steeg H, Dollé MET, Vermeij WP, Hoeijmakers JHJ, Essers J, van der Pluijm I, Danser AHJ, Roks AJM. Wu H, et al. Clin Sci (Lond). 2017 Jul 13;131(15):1941-1953. doi: 10.1042/CS20170026. Print 2017 Aug 1. Clin Sci (Lond). 2017. PMID: 28620011
Local endothelial DNA repair deficiency causes aging-resembling endothelial-specific dysfunction.
Bautista-Niño PK, Portilla-Fernandez E, Rubio-Beltrán E, van der Linden JJ, de Vries R, van Veghel R, de Boer M, Durik M, Ridwan Y, Brandt R, Essers J, Menzies RI, Thomas R, de Bruin A, Duncker DJ, van Beusekom HMM, Ghanbari M, Hoeijmakers JHJ, Sedlacek R, Touyz RM, Montezano AC, van der Pluijm I, Danser AHJ, Haanes KA, Roks AJM. Bautista-Niño PK, et al. Clin Sci (Lond). 2020 Apr 17;134(7):727-746. doi: 10.1042/CS20190124. Clin Sci (Lond). 2020. PMID: 32202295
Phosphodiesterase 1 regulation is a key mechanism in vascular aging.
Bautista Niño PK, Durik M, Danser AH, de Vries R, Musterd-Bhaggoe UM, Meima ME, Kavousi M, Ghanbari M, Hoeijmakers JH, O'Donnell CJ, Franceschini N, Janssen GM, De Mey JG, Liu Y, Shanahan CM, Franco OH, Dehghan A, Roks AJ. Bautista Niño PK, et al. Clin Sci (Lond). 2015 Dec;129(12):1061-75. doi: 10.1042/CS20140753. Epub 2015 Jun 25. Clin Sci (Lond). 2015. PMID: 26464516
20 results