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Page 1
The role of fMRI in drug development.
Carmichael O, Schwarz AJ, Chatham CH, Scott D, Turner JA, Upadhyay J, Coimbra A, Goodman JA, Baumgartner R, English BA, Apolzan JW, Shankapal P, Hawkins KR. Carmichael O, et al. Among authors: baumgartner r. Drug Discov Today. 2018 Feb;23(2):333-348. doi: 10.1016/j.drudis.2017.11.012. Epub 2017 Nov 15. Drug Discov Today. 2018. PMID: 29154758 Free PMC article. Review.
Improved characterization of BOLD responses for evoked sensory stimuli.
Upadhyay J, Pendse G, Anderson J, Schwarz AJ, Baumgartner R, Coimbra A, Bishop J, Knudsen J, George E, Grachev I, Iyengar S, Bleakman D, Hargreaves R, Borsook D, Becerra L. Upadhyay J, et al. Among authors: baumgartner r. Neuroimage. 2010 Feb 1;49(3):2275-86. doi: 10.1016/j.neuroimage.2009.10.053. Epub 2009 Oct 23. Neuroimage. 2010. PMID: 19854280
A procedural framework for good imaging practice in pharmacological fMRI studies applied to drug development #2: protocol optimization and best practices.
Schwarz AJ, Becerra L, Upadhyay J, Anderson J, Baumgartner R, Coimbra A, Evelhoch J, Hargreaves R, Robertson B, Iyengar S, Tauscher J, Bleakman D, Borsook D. Schwarz AJ, et al. Among authors: baumgartner r. Drug Discov Today. 2011 Aug;16(15-16):671-82. doi: 10.1016/j.drudis.2011.03.011. Epub 2011 Apr 6. Drug Discov Today. 2011. PMID: 21477664 Review.
A procedural framework for good imaging practice in pharmacological fMRI studies applied to drug development #1: processes and requirements.
Schwarz AJ, Becerra L, Upadhyay J, Anderson J, Baumgartner R, Coimbra A, Evelhoch J, Hargreaves R, Robertson B, Iyengar S, Tauscher J, Bleakman D, Borsook D. Schwarz AJ, et al. Among authors: baumgartner r. Drug Discov Today. 2011 Jul;16(13-14):583-93. doi: 10.1016/j.drudis.2011.05.006. Epub 2011 May 24. Drug Discov Today. 2011. PMID: 21635967 Review.
Imaging drugs with and without clinical analgesic efficacy.
Upadhyay J, Anderson J, Schwarz AJ, Coimbra A, Baumgartner R, Pendse G, George E, Nutile L, Wallin D, Bishop J, Neni S, Maier G, Iyengar S, Evelhoch JL, Bleakman D, Hargreaves R, Becerra L, Borsook D. Upadhyay J, et al. Among authors: baumgartner r. Neuropsychopharmacology. 2011 Dec;36(13):2659-73. doi: 10.1038/npp.2011.156. Epub 2011 Aug 17. Neuropsychopharmacology. 2011. PMID: 21849979 Free PMC article. Clinical Trial.
Modulation of CNS pain circuitry by intravenous and sublingual doses of buprenorphine.
Upadhyay J, Anderson J, Baumgartner R, Coimbra A, Schwarz AJ, Pendse G, Wallin D, Nutile L, Bishop J, George E, Elman I, Sunkaraneni S, Maier G, Iyengar S, Evelhoch JL, Bleakman D, Hargreaves R, Becerra L, Borsook D. Upadhyay J, et al. Among authors: baumgartner r. Neuroimage. 2012 Feb 15;59(4):3762-73. doi: 10.1016/j.neuroimage.2011.11.034. Epub 2011 Nov 18. Neuroimage. 2012. PMID: 22119647
Decision-making using fMRI in clinical drug development: revisiting NK-1 receptor antagonists for pain.
Borsook D, Upadhyay J, Klimas M, Schwarz AJ, Coimbra A, Baumgartner R, George E, Potter WZ, Large T, Bleakman D, Evelhoch J, Iyengar S, Becerra L, Hargreaves RJ. Borsook D, et al. Among authors: baumgartner r. Drug Discov Today. 2012 Sep;17(17-18):964-73. doi: 10.1016/j.drudis.2012.05.004. Epub 2012 May 10. Drug Discov Today. 2012. PMID: 22579743 Review.
1,004 results