Bauman DR - Search Results

1

Evaluation of selective inhibitors of 11β-HSD1 for the treatment of hypertension.

Bauman DR, Whitehead A, Contino LC, Cui J, Garcia-Calvo M, Gu X, Kevin N, Ma X, Pai LY, Shah K, Shen X, Stribling S, Zokian HJ, Metzger J, Shevell DE, Waddell ST. Bauman DR, et al. Bioorg Med Chem Lett. 2013 Jun 15;23(12):3650-3. doi: 10.1016/j.bmcl.2013.03.011. Epub 2013 Mar 22. Bioorg Med Chem Lett. 2013. PMID: 23659858

2

Discovery of the First Non-cGMP Mimetic Small Molecule Activators of cGMP-Dependent Protein Kinase 1 α (PKG1α).

Hanisak J, Soriano A, Adam GC, Basso A, Bauman D, Bell D, Frank E, O'Donnell G, Tawa P, Verras A, Yu Y, Zhang L, Seganish WM. Hanisak J, et al. ACS Med Chem Lett. 2021 Jul 16;12(8):1275-1282. doi: 10.1021/acsmedchemlett.1c00264. eCollection 2021 Aug 12. ACS Med Chem Lett. 2021. PMID: 34413956 Free PMC article.

3

Mechanistic insights on novel small molecule allosteric activators of cGMP-dependent protein kinase PKG1α.

Tawa P, Zhang L, Metwally E, Hou Y, McCoy MA, Seganish WM, Zhang R, Frank E, Sheth P, Hanisak J, Sondey C, Bauman D, Soriano A. Tawa P, et al. J Biol Chem. 2022 Sep;298(9):102284. doi: 10.1016/j.jbc.2022.102284. Epub 2022 Jul 19. J Biol Chem. 2022. PMID: 35868561 Free PMC article.

4

Non-stereo-selective cytosolic human brain tissue 3-ketosteroid reductase is refractory to inhibition by AKR1C inhibitors.

Steckelbroeck S, Lütjohann D, Bauman DR, Ludwig M, Friedl A, Hans VH, Penning TM, Klingmüller D. Steckelbroeck S, et al. Among authors: bauman dr. Biochim Biophys Acta. 2010 Nov;1801(11):1221-31. doi: 10.1016/j.bbalip.2010.07.005. Epub 2010 Jul 29. Biochim Biophys Acta. 2010. PMID: 20673851 Free PMC article.

5

Human type 3 3alpha-hydroxysteroid dehydrogenase (aldo-keto reductase 1C2) and androgen metabolism in prostate cells.

Rizner TL, Lin HK, Peehl DM, Steckelbroeck S, Bauman DR, Penning TM. Rizner TL, et al. Among authors: bauman dr. Endocrinology. 2003 Jul;144(7):2922-32. doi: 10.1210/en.2002-0032. Endocrinology. 2003. PMID: 12810547

6

Aldo-keto reductase (AKR) 1C3: role in prostate disease and the development of specific inhibitors.

Penning TM, Steckelbroeck S, Bauman DR, Miller MW, Jin Y, Peehl DM, Fung KM, Lin HK. Penning TM, et al. Among authors: bauman dr. Mol Cell Endocrinol. 2006 Mar 27;248(1-2):182-91. doi: 10.1016/j.mce.2005.12.009. Epub 2006 Jan 18. Mol Cell Endocrinol. 2006. PMID: 16417966

7

Transcript profiling of the androgen signal in normal prostate, benign prostatic hyperplasia, and prostate cancer.

Bauman DR, Steckelbroeck S, Peehl DM, Penning TM. Bauman DR, et al. Endocrinology. 2006 Dec;147(12):5806-16. doi: 10.1210/en.2006-0627. Epub 2006 Sep 7. Endocrinology. 2006. PMID: 16959841

8

Identification of the major oxidative 3alpha-hydroxysteroid dehydrogenase in human prostate that converts 5alpha-androstane-3alpha,17beta-diol to 5alpha-dihydrotestosterone: a potential therapeutic target for androgen-dependent disease.

Bauman DR, Steckelbroeck S, Williams MV, Peehl DM, Penning TM. Bauman DR, et al. Mol Endocrinol. 2006 Feb;20(2):444-58. doi: 10.1210/me.2005-0287. Epub 2005 Sep 22. Mol Endocrinol. 2006. PMID: 16179381

9

Identification of the molecular switch that regulates access of 5alpha-DHT to the androgen receptor.

Penning TM, Bauman DR, Jin Y, Rizner TL. Penning TM, et al. Among authors: bauman dr. Mol Cell Endocrinol. 2007 Feb;265-266:77-82. doi: 10.1016/j.mce.2006.12.007. Epub 2007 Jan 16. Mol Cell Endocrinol. 2007. PMID: 17223255 Free PMC article. Review.

10

Pre-receptor regulation of the androgen receptor.

Penning TM, Jin Y, Rizner TL, Bauman DR. Penning TM, et al. Among authors: bauman dr. Mol Cell Endocrinol. 2008 Jan 16;281(1-2):1-8. doi: 10.1016/j.mce.2007.10.008. Epub 2007 Oct 22. Mol Cell Endocrinol. 2008. PMID: 18060684 Free PMC article. Review.

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