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Hundreds of dual-stage antimalarial molecules discovered by a functional gametocyte screen.
Miguel-Blanco C, Molina I, Bardera AI, Díaz B, de Las Heras L, Lozano S, González C, Rodrigues J, Delves MJ, Ruecker A, Colmenarejo G, Viera S, Martínez-Martínez MS, Fernández E, Baum J, Sinden RE, Herreros E. Miguel-Blanco C, et al. Among authors: baum j. Nat Commun. 2017 May 17;8:15160. doi: 10.1038/ncomms15160. Nat Commun. 2017. PMID: 28513586 Free PMC article.
Development of a Photo-Cross-Linkable Diaminoquinazoline Inhibitor for Target Identification in Plasmodium falciparum.
Lubin AS, Rueda-Zubiaurre A, Matthews H, Baumann H, Fisher FR, Morales-Sanfrutos J, Hadavizadeh KS, Nardella F, Tate EW, Baum J, Scherf A, Fuchter MJ. Lubin AS, et al. Among authors: baum j. ACS Infect Dis. 2018 Apr 13;4(4):523-530. doi: 10.1021/acsinfecdis.7b00228. Epub 2018 Feb 5. ACS Infect Dis. 2018. PMID: 29377668 Free PMC article.
A high throughput screen for next-generation leads targeting malaria parasite transmission.
Delves MJ, Miguel-Blanco C, Matthews H, Molina I, Ruecker A, Yahiya S, Straschil U, Abraham M, León ML, Fischer OJ, Rueda-Zubiaurre A, Brandt JR, Cortés Á, Barnard A, Fuchter MJ, Calderón F, Winzeler EA, Sinden RE, Herreros E, Gamo FJ, Baum J. Delves MJ, et al. Among authors: baum j. Nat Commun. 2018 Sep 18;9(1):3805. doi: 10.1038/s41467-018-05777-2. Nat Commun. 2018. PMID: 30228275 Free PMC article.
Plasmodium myosin A drives parasite invasion by an atypical force generating mechanism.
Robert-Paganin J, Robblee JP, Auguin D, Blake TCA, Bookwalter CS, Krementsova EB, Moussaoui D, Previs MJ, Jousset G, Baum J, Trybus KM, Houdusse A. Robert-Paganin J, et al. Among authors: baum j. Nat Commun. 2019 Jul 23;10(1):3286. doi: 10.1038/s41467-019-11120-0. Nat Commun. 2019. PMID: 31337750 Free PMC article.
1,231 results