Baum J - Search Results

1

A Biosynthetic Platform for Antimalarial Drug Discovery.

Wilkinson MD, Lai HE, Freemont PS, Baum J. Wilkinson MD, et al. Among authors: baum j. Antimicrob Agents Chemother. 2020 Apr 21;64(5):e02129-19. doi: 10.1128/AAC.02129-19. Print 2020 Apr 21. Antimicrob Agents Chemother. 2020. PMID: 32152076 Free PMC article.

2

Disassembly activity of actin-depolymerizing factor (ADF) is associated with distinct cellular processes in apicomplexan parasites.

Haase S, Zimmermann D, Olshina MA, Wilkinson M, Fisher F, Tan YH, Stewart RJ, Tonkin CJ, Wong W, Kovar DR, Baum J. Haase S, et al. Among authors: baum j. Mol Biol Cell. 2015 Sep 1;26(17):3001-12. doi: 10.1091/mbc.E14-10-1427. Epub 2015 Jul 8. Mol Biol Cell. 2015. PMID: 26157165 Free PMC article.

3

Macrolides rapidly inhibit red blood cell invasion by the human malaria parasite, Plasmodium falciparum.

Wilson DW, Goodman CD, Sleebs BE, Weiss GE, de Jong NW, Angrisano F, Langer C, Baum J, Crabb BS, Gilson PR, McFadden GI, Beeson JG. Wilson DW, et al. Among authors: baum j. BMC Biol. 2015 Jul 18;13:52. doi: 10.1186/s12915-015-0162-0. BMC Biol. 2015. PMID: 26187647 Free PMC article.

4

Truncated Latrunculins as Actin Inhibitors Targeting Plasmodium falciparum Motility and Host Cell Invasion.

Johnson S, Rahmani R, Drew DR, Williams MJ, Wilkinson M, Tan YH, Huang JX, Tonkin CJ, Beeson JG, Baum J, Smith BJ, Baell JB. Johnson S, et al. Among authors: baum j. J Med Chem. 2016 Dec 22;59(24):10994-11005. doi: 10.1021/acs.jmedchem.6b01109. Epub 2016 Dec 2. J Med Chem. 2016. PMID: 28002959 Free PMC article.

5

The antimalarial screening landscape-looking beyond the asexual blood stage.

Yahiya S, Rueda-Zubiaurre A, Delves MJ, Fuchter MJ, Baum J. Yahiya S, et al. Among authors: baum j. Curr Opin Chem Biol. 2019 Jun;50:1-9. doi: 10.1016/j.cbpa.2019.01.029. Epub 2019 Mar 12. Curr Opin Chem Biol. 2019. PMID: 30875617 Free PMC article. Review.

6

Quantitative and rapid Plasmodium falciparum malaria diagnosis and artemisinin-resistance detection using a CMOS Lab-on-Chip platform.

Malpartida-Cardenas K, Miscourides N, Rodriguez-Manzano J, Yu LS, Moser N, Baum J, Georgiou P. Malpartida-Cardenas K, et al. Among authors: baum j. Biosens Bioelectron. 2019 Dec 1;145:111678. doi: 10.1016/j.bios.2019.111678. Epub 2019 Sep 7. Biosens Bioelectron. 2019. PMID: 31541787 Free PMC article.

7

Screen of traditional soup broths with reported antipyretic activity towards the discovery of potential antimalarials.

Children of Eden Primary School; Straschil U, Witmer K, Delves MJ, Marks SD, Baum J. Children of Eden Primary School, et al. Among authors: baum j. Arch Dis Child. 2019 Dec;104(12):1138-1142. doi: 10.1136/archdischild-2019-317590. Arch Dis Child. 2019. PMID: 31744794 Free PMC article.

8

Structure-Activity Studies of Truncated Latrunculin Analogues with Antimalarial Activity.

Varghese S, Rahmani R, Drew DR, Beeson JG, Baum J, Smith BJ, Baell JB. Varghese S, et al. Among authors: baum j. ChemMedChem. 2021 Feb 17;16(4):679-693. doi: 10.1002/cmdc.202000399. Epub 2020 Nov 10. ChemMedChem. 2021. PMID: 32929894

9

A machine learning approach to define antimalarial drug action from heterogeneous cell-based screens.

Ashdown GW, Dimon M, Fan M, Sánchez-Román Terán F, Witmer K, Gaboriau DCA, Armstrong Z, Ando DM, Baum J. Ashdown GW, et al. Among authors: baum j. Sci Adv. 2020 Sep 25;6(39):eaba9338. doi: 10.1126/sciadv.aba9338. Print 2020 Sep. Sci Adv. 2020. PMID: 32978158 Free PMC article.

10

Transmission of Artemisinin-Resistant Malaria Parasites to Mosquitoes under Antimalarial Drug Pressure.

Witmer K, Dahalan FA, Delves MJ, Yahiya S, Watson OJ, Straschil U, Chiwcharoen D, Sornboon B, Pukrittayakamee S, Pearson RD, Howick VM, Lawniczak MKN, White NJ, Dondorp AM, Okell LC, Chotivanich K, Ruecker A, Baum J. Witmer K, et al. Among authors: baum j. Antimicrob Agents Chemother. 2020 Dec 16;65(1):e00898-20. doi: 10.1128/AAC.00898-20. Print 2020 Dec 16. Antimicrob Agents Chemother. 2020. PMID: 33139275 Free PMC article.

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