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Endoplasmic Reticulum Stress-Induced Upregulation of STARD1 Promotes Acetaminophen-Induced Acute Liver Failure.
Torres S, Baulies A, Insausti-Urkia N, Alarcón-Vila C, Fucho R, Solsona-Vilarrasa E, Núñez S, Robles D, Ribas V, Wakefield L, Grompe M, Lucena MI, Andrade RJ, Win S, Aung TA, Kaplowitz N, García-Ruiz C, Fernández-Checa JC. Torres S, et al. Among authors: baulies a. Gastroenterology. 2019 Aug;157(2):552-568. doi: 10.1053/j.gastro.2019.04.023. Epub 2019 Apr 25. Gastroenterology. 2019. PMID: 31029706 Free article.
ASMase is required for chronic alcohol induced hepatic endoplasmic reticulum stress and mitochondrial cholesterol loading.
Fernandez A, Matias N, Fucho R, Ribas V, Von Montfort C, Nuño N, Baulies A, Martinez L, Tarrats N, Mari M, Colell A, Morales A, Dubuquoy L, Mathurin P, Bataller R, Caballeria J, Elena M, Balsinde J, Kaplowitz N, Garcia-Ruiz C, Fernandez-Checa JC. Fernandez A, et al. Among authors: baulies a. J Hepatol. 2013 Oct;59(4):805-13. doi: 10.1016/j.jhep.2013.05.023. Epub 2013 May 23. J Hepatol. 2013. PMID: 23707365 Free PMC article.
STARD1 promotes NASH-driven HCC by sustaining the generation of bile acids through the alternative mitochondrial pathway.
Conde de la Rosa L, Garcia-Ruiz C, Vallejo C, Baulies A, Nuñez S, Monte MJ, Marin JJG, Baila-Rueda L, Cenarro A, Civeira F, Fuster J, Garcia-Valdecasas JC, Ferrer J, Karin M, Ribas V, Fernandez-Checa JC. Conde de la Rosa L, et al. Among authors: baulies a. J Hepatol. 2021 Jun;74(6):1429-1441. doi: 10.1016/j.jhep.2021.01.028. Epub 2021 Jan 27. J Hepatol. 2021. PMID: 33515644 Free PMC article.
ASMase regulates autophagy and lysosomal membrane permeabilization and its inhibition prevents early stage non-alcoholic steatohepatitis.
Fucho R, Martínez L, Baulies A, Torres S, Tarrats N, Fernandez A, Ribas V, Astudillo AM, Balsinde J, Garcia-Rovés P, Elena M, Bergheim I, Lotersztajn S, Trautwein C, Appelqvist H, Paton AW, Paton JC, Czaja MJ, Kaplowitz N, Fernandez-Checa JC, García-Ruiz C. Fucho R, et al. Among authors: baulies a. J Hepatol. 2014 Nov;61(5):1126-34. doi: 10.1016/j.jhep.2014.06.009. Epub 2014 Jun 16. J Hepatol. 2014. PMID: 24946279 Free PMC article.
Mitochondrial Cholesterol and the Paradox in Cell Death.
García-Ruiz C, Ribas V, Baulies A, Fernández-Checa JC. García-Ruiz C, et al. Among authors: baulies a. Handb Exp Pharmacol. 2017;240:189-210. doi: 10.1007/164_2016_110. Handb Exp Pharmacol. 2017. PMID: 28035533 Review.
Engineered fibroblast growth factor 19 protects from acetaminophen-induced liver injury and stimulates aged liver regeneration in mice.
Alvarez-Sola G, Uriarte I, Latasa MU, Jimenez M, Barcena-Varela M, Santamaría E, Urtasun R, Rodriguez-Ortigosa C, Prieto J, Corrales FJ, Baulies A, García-Ruiz C, Fernandez-Checa JC, Berraondo P, Fernandez-Barrena MG, Berasain C, Avila MA. Alvarez-Sola G, et al. Among authors: baulies a. Cell Death Dis. 2017 Oct 5;8(10):e3083. doi: 10.1038/cddis.2017.480. Cell Death Dis. 2017. PMID: 28981086 Free PMC article.
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