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Islet-reactive CD8+ T cell frequencies in the pancreas, but not in blood, distinguish type 1 diabetic patients from healthy donors.
Culina S, Lalanne AI, Afonso G, Cerosaletti K, Pinto S, Sebastiani G, Kuranda K, Nigi L, Eugster A, Østerbye T, Maugein A, McLaren JE, Ladell K, Larger E, Beressi JP, Lissina A, Appay V, Davidson HW, Buus S, Price DA, Kuhn M, Bonifacio E, Battaglia M, Caillat-Zucman S, Dotta F, Scharfmann R, Kyewski B, Mallone R; ImMaDiab Study Group. Culina S, et al. Among authors: battaglia m. Sci Immunol. 2018 Feb 2;3(20):eaao4013. doi: 10.1126/sciimmunol.aao4013. Sci Immunol. 2018. PMID: 29429978 Free PMC article.
Expansion of Th17 cells and functional defects in T regulatory cells are key features of the pancreatic lymph nodes in patients with type 1 diabetes.
Ferraro A, Socci C, Stabilini A, Valle A, Monti P, Piemonti L, Nano R, Olek S, Maffi P, Scavini M, Secchi A, Staudacher C, Bonifacio E, Battaglia M. Ferraro A, et al. Among authors: battaglia m. Diabetes. 2011 Nov;60(11):2903-13. doi: 10.2337/db11-0090. Epub 2011 Sep 6. Diabetes. 2011. PMID: 21896932 Free PMC article.
Reduction of circulating neutrophils precedes and accompanies type 1 diabetes.
Valle A, Giamporcaro GM, Scavini M, Stabilini A, Grogan P, Bianconi E, Sebastiani G, Masini M, Maugeri N, Porretti L, Bonfanti R, Meschi F, De Pellegrin M, Lesma A, Rossini S, Piemonti L, Marchetti P, Dotta F, Bosi E, Battaglia M. Valle A, et al. Among authors: battaglia m. Diabetes. 2013 Jun;62(6):2072-7. doi: 10.2337/db12-1345. Epub 2013 Jan 24. Diabetes. 2013. PMID: 23349491 Free PMC article.
1,277 results