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HNRNPA1-induced spliceopathy in a transgenic mouse model of myotonic dystrophy.
Li M, Zhuang Y, Batra R, Thomas JD, Li M, Nutter CA, Scotti MM, Carter HA, Wang ZJ, Huang XS, Pu CQ, Swanson MS, Xie W. Li M, et al. Among authors: batra r. Proc Natl Acad Sci U S A. 2020 Mar 10;117(10):5472-5477. doi: 10.1073/pnas.1907297117. Epub 2020 Feb 21. Proc Natl Acad Sci U S A. 2020. PMID: 32086392 Free PMC article.
The sustained expression of Cas9 targeting toxic RNAs reverses disease phenotypes in mouse models of myotonic dystrophy type 1.
Batra R, Nelles DA, Roth DM, Krach F, Nutter CA, Tadokoro T, Thomas JD, Sznajder ŁJ, Blue SM, Gutierrez HL, Liu P, Aigner S, Platoshyn O, Miyanohara A, Marsala M, Swanson MS, Yeo GW. Batra R, et al. Nat Biomed Eng. 2021 Feb;5(2):157-168. doi: 10.1038/s41551-020-00607-7. Epub 2020 Sep 14. Nat Biomed Eng. 2021. PMID: 32929188 Free PMC article.
Muscleblind-like 2-mediated alternative splicing in the developing brain and dysregulation in myotonic dystrophy.
Charizanis K, Lee KY, Batra R, Goodwin M, Zhang C, Yuan Y, Shiue L, Cline M, Scotti MM, Xia G, Kumar A, Ashizawa T, Clark HB, Kimura T, Takahashi MP, Fujimura H, Jinnai K, Yoshikawa H, Gomes-Pereira M, Gourdon G, Sakai N, Nishino S, Foster TC, Ares M Jr, Darnell RB, Swanson MS. Charizanis K, et al. Among authors: batra r. Neuron. 2012 Aug 9;75(3):437-50. doi: 10.1016/j.neuron.2012.05.029. Neuron. 2012. PMID: 22884328 Free PMC article.
Compound loss of muscleblind-like function in myotonic dystrophy.
Lee KY, Li M, Manchanda M, Batra R, Charizanis K, Mohan A, Warren SA, Chamberlain CM, Finn D, Hong H, Ashraf H, Kasahara H, Ranum LP, Swanson MS. Lee KY, et al. Among authors: batra r. EMBO Mol Med. 2013 Dec;5(12):1887-900. doi: 10.1002/emmm.201303275. Epub 2013 Oct 8. EMBO Mol Med. 2013. PMID: 24293317 Free PMC article.
MBNL Sequestration by Toxic RNAs and RNA Misprocessing in the Myotonic Dystrophy Brain.
Goodwin M, Mohan A, Batra R, Lee KY, Charizanis K, Fernández Gómez FJ, Eddarkaoui S, Sergeant N, Buée L, Kimura T, Clark HB, Dalton J, Takamura K, Weyn-Vanhentenryck SM, Zhang C, Reid T, Ranum LP, Day JW, Swanson MS. Goodwin M, et al. Among authors: batra r. Cell Rep. 2015 Aug 18;12(7):1159-68. doi: 10.1016/j.celrep.2015.07.029. Epub 2015 Aug 6. Cell Rep. 2015. PMID: 26257173 Free PMC article.
Developments in RNA splicing and disease.
Poulos MG, Batra R, Charizanis K, Swanson MS. Poulos MG, et al. Among authors: batra r. Cold Spring Harb Perspect Biol. 2011 Jan 1;3(1):a000778. doi: 10.1101/cshperspect.a000778. Cold Spring Harb Perspect Biol. 2011. PMID: 21084389 Free PMC article. Review.
554 results