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A positive allosteric modulator of mGluR5 promotes neuroprotective effects in mouse models of Alzheimer's disease.
Bellozi PMQ, Gomes GF, da Silva MCM, Lima IVA, Batista CRÁ, Carneiro Junior WO, Dória JG, Vieira ÉLM, Vieira RP, de Freitas RP, Ferreira CN, Candelario-Jalil E, Wyss-Coray T, Ribeiro FM, de Oliveira ACP. Bellozi PMQ, et al. Among authors: batista cra. Neuropharmacology. 2019 Dec 1;160:107785. doi: 10.1016/j.neuropharm.2019.107785. Epub 2019 Sep 18. Neuropharmacology. 2019. PMID: 31541651
Role of Microglia TLRs in Neurodegeneration.
Fiebich BL, Batista CRA, Saliba SW, Yousif NM, de Oliveira ACP. Fiebich BL, et al. Among authors: batista cra. Front Cell Neurosci. 2018 Oct 2;12:329. doi: 10.3389/fncel.2018.00329. eCollection 2018. Front Cell Neurosci. 2018. PMID: 30333729 Free PMC article.
Metformin effect in models of inflammation is associated with activation of ATP-dependent potassium channels and inhibition of tumor necrosis factor-α production.
Augusto PSA, Matsui TC, Braga AV, Rodrigues FF, Morais MI, Dutra MMGB, Batista CRA, Melo ISF, Costa SOAM, Bertollo CM, Coelho MM, Machado RR. Augusto PSA, et al. Among authors: batista cra. Inflammopharmacology. 2022 Feb;30(1):233-241. doi: 10.1007/s10787-021-00899-4. Epub 2021 Nov 30. Inflammopharmacology. 2022. PMID: 34850313
The phthalimide analogues N-3-hydroxypropylphthalimide and N-carboxymethyl-3-nitrophthalimide exhibit activity in experimental models of inflammatory and neuropathic pain.
Batista CRA, Godin AM, Melo ISF, Coura GME, Matsui TC, Dutra MMGB, Brito AMS, Canhestro WG, Alves RJ, Araújo DP, de Fátima Â, Machado RR, Coelho MM. Batista CRA, et al. Pharmacol Rep. 2019 Dec;71(6):1177-1183. doi: 10.1016/j.pharep.2019.08.001. Epub 2019 Aug 17. Pharmacol Rep. 2019. PMID: 31669881
Metformin antinociceptive effect in models of nociceptive and neuropathic pain is partially mediated by activation of opioidergic mechanisms.
Augusto PSA, Braga AV, Rodrigues FF, Morais MI, Dutra MMGB, Batista CRA, Melo ISF, Costa SOAM, Goulart FA, Coelho MM, Machado RR. Augusto PSA, et al. Among authors: batista cra. Eur J Pharmacol. 2019 Sep 5;858:172497. doi: 10.1016/j.ejphar.2019.172497. Epub 2019 Jun 22. Eur J Pharmacol. 2019. PMID: 31238066 Free article.
Activities of 2-phthalimidethyl nitrate and 2-phthalimidethanol in the models of nociceptive response and edema induced by formaldehyde in mice and preliminary investigation of the underlying mechanisms.
Godin AM, Araújo DP, César IC, Menezes RR, Brito AM, Melo IS, Coura GM, Bastos LF, Almeida MO, Byrro RM, Matsui TC, Batista CR, Pianetti GA, de Fátima Â, Machado RR, Coelho MM. Godin AM, et al. Eur J Pharmacol. 2015 Jun 5;756:59-66. doi: 10.1016/j.ejphar.2015.02.052. Epub 2015 Mar 17. Eur J Pharmacol. 2015. PMID: 25794846