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Ruthenium (II) complexes with N, O-chelating proline and threonine ligands cause selective cytotoxicity by the induction of genomic instability, cell cycle arrest and apoptosis in breast and prostate tumor cells.
de Sousa IH, Campos VNS, Vale AAM, Maciel-Silva VL, Leite CM, Lopes AJO, Mourão PS, das Chagas Alves Lima F, Batista AA, de Azevedo Dos Santos APS, Almeida MAP, Pereira SRF. de Sousa IH, et al. Among authors: batista aa. Toxicol In Vitro. 2020 Feb;62:104679. doi: 10.1016/j.tiv.2019.104679. Epub 2019 Oct 30. Toxicol In Vitro. 2020. PMID: 31676337
Antitumor effectiveness and mechanism of action of Ru(II)/amino acid/diphosphine complexes in the peritoneal carcinomatosis progression.
Mello-Andrade F, da Costa WL, Pires WC, Pereira FC, Cardoso CG, Lino-Junior RS, Irusta VRC, Carneiro CC, de Melo-Reis PR, Castro CH, Almeida MAP, Batista AA, Silveira-Lacerda EP. Mello-Andrade F, et al. Among authors: batista aa. Tumour Biol. 2017 Oct;39(10):1010428317695933. doi: 10.1177/1010428317695933. Tumour Biol. 2017. PMID: 29019283 Free article.
Acute toxic effects of ruthenium (II)/amino acid/diphosphine complexes on Swiss mice and zebrafish embryos.
Mello-Andrade F, Cardoso CG, Silva CRE, Chen-Chen L, Melo-Reis PR, Lima AP, Oliveira R, Ferraz IBM, Grisolia CK, Almeida MAP, Batista AA, Silveira-Lacerda EP. Mello-Andrade F, et al. Among authors: batista aa. Biomed Pharmacother. 2018 Nov;107:1082-1092. doi: 10.1016/j.biopha.2018.08.051. Epub 2018 Aug 25. Biomed Pharmacother. 2018. PMID: 30257320
Ru(II)-Based Amino Acid Complexes Show Promise for Leukemia Treatment: Cytotoxicity and Some Light on their Mechanism of Action.
de Lima AP, Almeida MAP, Mello-Andrade F, de Castro Pereira F, Pires WC, Abreu DC, de Souza Velozo-Sá V, Batista AA, de Paula Silveira-Lacerda E. de Lima AP, et al. Among authors: batista aa. Biol Trace Elem Res. 2020 Sep;197(1):123-131. doi: 10.1007/s12011-019-01976-0. Epub 2019 Nov 26. Biol Trace Elem Res. 2020. PMID: 31773484
Synthesis and structural characterization of a series of ternary copper(II)-L-dipeptide-neocuproine complexes. Study of their cytotoxicity against cancer cells including MDA-MB-231, triple negative breast cancer cells.
Alvarez N, Viña D, Leite CM, Mendes LFS, Batista AA, Ellena J, Costa-Filho AJ, Facchin G. Alvarez N, et al. Among authors: batista aa. J Inorg Biochem. 2020 Feb;203:110930. doi: 10.1016/j.jinorgbio.2019.110930. Epub 2019 Nov 18. J Inorg Biochem. 2020. PMID: 31812025
Heterobimetallic Ru(ii)/Fe(ii) complexes as potent anticancer agents against breast cancer cells, inducing apoptosis through multiple targets.
Guedes APM , Mello-Andrade F , Pires WC , de Sousa MAM , da Silva PFF , de Camargo MS , Gemeiner H , Amauri MA , Gomes Cardoso C , de Melo Reis PR , Silveira-Lacerda EP , Batista AA . Guedes APM , et al. Among authors: batista aa. Metallomics. 2020 Apr 1;12(4):547-561. doi: 10.1039/c9mt00272c. Epub 2020 Feb 28. Metallomics. 2020. PMID: 32108850
148 results