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Page 1
Synergistic cancer immunotherapy combines MVA-CD40L induced innate and adaptive immunity with tumor targeting antibodies.
Medina-Echeverz J, Hinterberger M, Testori M, Geiger M, Giessel R, Bathke B, Kassub R, Gräbnitz F, Fiore G, Wennier ST, Chaplin P, Suter M, Hochrein H, Lauterbach H. Medina-Echeverz J, et al. Among authors: bathke b. Nat Commun. 2019 Nov 6;10(1):5041. doi: 10.1038/s41467-019-12998-6. Nat Commun. 2019. PMID: 31695037 Free PMC article.
A major role for TLR8 in the recognition of vaccinia viral DNA by murine pDC?
Bauer S, Bathke B, Lauterbach H, Pätzold J, Kassub R, Luber CA, Schlatter B, Hamm S, Chaplin P, Suter M, Hochrein H. Bauer S, et al. Among authors: bathke b. Proc Natl Acad Sci U S A. 2010 Sep 7;107(36):E139; author reply E140. doi: 10.1073/pnas.1008626107. Epub 2010 Aug 2. Proc Natl Acad Sci U S A. 2010. PMID: 20679190 Free PMC article. No abstract available.
Mouse CD8alpha+ DCs and human BDCA3+ DCs are major producers of IFN-lambda in response to poly IC.
Lauterbach H, Bathke B, Gilles S, Traidl-Hoffmann C, Luber CA, Fejer G, Freudenberg MA, Davey GM, Vremec D, Kallies A, Wu L, Shortman K, Chaplin P, Suter M, O'Keeffe M, Hochrein H. Lauterbach H, et al. Among authors: bathke b. J Exp Med. 2010 Nov 22;207(12):2703-17. doi: 10.1084/jem.20092720. Epub 2010 Oct 25. J Exp Med. 2010. PMID: 20975040 Free PMC article.
TLR13 recognizes bacterial 23S rRNA devoid of erythromycin resistance-forming modification.
Oldenburg M, Krüger A, Ferstl R, Kaufmann A, Nees G, Sigmund A, Bathke B, Lauterbach H, Suter M, Dreher S, Koedel U, Akira S, Kawai T, Buer J, Wagner H, Bauer S, Hochrein H, Kirschning CJ. Oldenburg M, et al. Among authors: bathke b. Science. 2012 Aug 31;337(6098):1111-5. doi: 10.1126/science.1220363. Epub 2012 Jul 19. Science. 2012. PMID: 22821982
Intratumoral virotherapy with 4-1BBL armed modified vaccinia Ankara eradicates solid tumors and promotes protective immune memory.
Hinterberger M, Giessel R, Fiore G, Graebnitz F, Bathke B, Wennier S, Chaplin P, Melero I, Suter M, Lauterbach H, Berraondo P, Hochrein H, Medina-Echeverz J. Hinterberger M, et al. Among authors: bathke b. J Immunother Cancer. 2021 Feb;9(2):e001586. doi: 10.1136/jitc-2020-001586. J Immunother Cancer. 2021. PMID: 33579736 Free PMC article.
Preclinical development of a first-in-class vaccine encoding HER2, Brachyury and CD40L for antibody enhanced tumor eradication.
Hinterberger M, Endt K, Bathke B, Habjan M, Heiseke A, Schweneker M, Von Rohrscheidt J, Atay C, Chaplin P, Kalla M, Hausmann J, Schmittwolf C, Lauterbach H, Volkmann A, Hochrein H, Medina-Echeverz J. Hinterberger M, et al. Among authors: bathke b. Sci Rep. 2023 Mar 30;13(1):5162. doi: 10.1038/s41598-023-32060-2. Sci Rep. 2023. PMID: 36997583 Free PMC article.