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In vitro generation of mouse morula-like cells.
Li H, Chang L, Wu J, Huang J, Guan W, Bates LE, Stuart HT, Guo M, Zhang P, Huang B, Chen C, Zhang M, Chen J, Min M, Wu G, Hutchins AP, Silva JCR. Li H, et al. Among authors: bates le. Dev Cell. 2023 Nov 20;58(22):2510-2527.e7. doi: 10.1016/j.devcel.2023.09.013. Epub 2023 Oct 23. Dev Cell. 2023. PMID: 37875119
Auxin-degron system identifies immediate mechanisms of OCT4.
Bates LE, Alves MRP, Silva JCR. Bates LE, et al. Stem Cell Reports. 2021 Jul 13;16(7):1818-1831. doi: 10.1016/j.stemcr.2021.05.016. Epub 2021 Jun 17. Stem Cell Reports. 2021. PMID: 34143975 Free PMC article.
OCT4 induces embryonic pluripotency via STAT3 signaling and metabolic mechanisms.
Stirparo GG, Kurowski A, Yanagida A, Bates LE, Strawbridge SE, Hladkou S, Stuart HT, Boroviak TE, Silva JCR, Nichols J. Stirparo GG, et al. Among authors: bates le. Proc Natl Acad Sci U S A. 2021 Jan 19;118(3):e2008890118. doi: 10.1073/pnas.2008890118. Proc Natl Acad Sci U S A. 2021. PMID: 33452132 Free PMC article.
Sox2 modulation increases naïve pluripotency plasticity.
Tremble KC, Stirparo GG, Bates LE, Maskalenka K, Stuart HT, Jones K, Andersson-Rolf A, Radzisheuskaya A, Koo BK, Bertone P, Silva JCR. Tremble KC, et al. Among authors: bates le. iScience. 2021 Feb 6;24(3):102153. doi: 10.1016/j.isci.2021.102153. eCollection 2021 Mar 19. iScience. 2021. PMID: 33665571 Free PMC article.
Distinct Molecular Trajectories Converge to Induce Naive Pluripotency.
Stuart HT, Stirparo GG, Lohoff T, Bates LE, Kinoshita M, Lim CY, Sousa EJ, Maskalenka K, Radzisheuskaya A, Malcolm AA, Alves MRP, Lloyd RL, Nestorowa S, Humphreys P, Mansfield W, Reik W, Bertone P, Nichols J, Göttgens B, Silva JCR. Stuart HT, et al. Among authors: bates le. Cell Stem Cell. 2019 Sep 5;25(3):388-406.e8. doi: 10.1016/j.stem.2019.07.009. Epub 2019 Aug 15. Cell Stem Cell. 2019. PMID: 31422912 Free PMC article.
OCT4 activates a Suv39h1-repressive antisense lncRNA to couple histone H3 Lysine 9 methylation to pluripotency.
Bernard LD, Dubois A, Heurtier V, Fischer V, Gonzalez I, Chervova A, Tachtsidi A, Gil N, Owens N, Bates LE, Vandormael-Pournin S, Silva JCR, Ulitsky I, Cohen-Tannoudji M, Navarro P. Bernard LD, et al. Among authors: bates le. Nucleic Acids Res. 2022 Jul 22;50(13):7367-7379. doi: 10.1093/nar/gkac550. Nucleic Acids Res. 2022. PMID: 35762231 Free PMC article.
FRET-enhanced photostability allows improved single-molecule tracking of proteins and protein complexes in live mammalian cells.
Basu S, Needham LM, Lando D, Taylor EJR, Wohlfahrt KJ, Shah D, Boucher W, Tan YL, Bates LE, Tkachenko O, Cramard J, Lagerholm BC, Eggeling C, Hendrich B, Klenerman D, Lee SF, Laue ED. Basu S, et al. Among authors: bates le. Nat Commun. 2018 Jun 28;9(1):2520. doi: 10.1038/s41467-018-04486-0. Nat Commun. 2018. PMID: 29955052 Free PMC article.
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