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Page 1
Somatic TP53 mutations are preleukemic events in acute lymphoblastic leukemia.
Chitadze G, Stengel A, John-Klaua C, Bruckmüller J, Trautmann H, Kotrova M, Darzentas F, Kelm M, Pal K, Darzentas N, Bastian L, Kehden B, Wessels W, Ströh AS, Oberg HH, Altrock PM, Baer C, Meggendorfer M, Gökbuget N, Baldus CD, Haferlach C, Brüggemann M. Chitadze G, et al. Among authors: bastian l. Blood. 2023 Mar 30;141(13):1640-1644. doi: 10.1182/blood.2022017249. Blood. 2023. PMID: 36450137 Free PMC article. No abstract available.
Long non-coding RNAs defining major subtypes of B cell precursor acute lymphoblastic leukemia.
James AR, Schroeder MP, Neumann M, Bastian L, Eckert C, Gökbuget N, Tanchez JO, Schlee C, Isaakidis K, Schwartz S, Burmeister T, von Stackelberg A, Rieger MA, Göllner S, Horstman M, Schrappe M, Kirschner-Schwabe R, Brüggemann M, Müller-Tidow C, Serve H, Akalin A, Baldus CD. James AR, et al. Among authors: bastian l. J Hematol Oncol. 2019 Jan 14;12(1):8. doi: 10.1186/s13045-018-0692-3. J Hematol Oncol. 2019. PMID: 30642353 Free PMC article.
PAX5 biallelic genomic alterations define a novel subgroup of B-cell precursor acute lymphoblastic leukemia.
Bastian L, Schroeder MP, Eckert C, Schlee C, Tanchez JO, Kämpf S, Wagner DL, Schulze V, Isaakidis K, Lázaro-Navarro J, Hänzelmann S, James AR, Ekici A, Burmeister T, Schwartz S, Schrappe M, Horstmann M, Vosberg S, Krebs S, Blum H, Hecht J, Greif PA, Rieger MA, Brüggemann M, Gökbuget N, Neumann M, Baldus CD. Bastian L, et al. Leukemia. 2019 Aug;33(8):1895-1909. doi: 10.1038/s41375-019-0430-z. Epub 2019 Mar 6. Leukemia. 2019. PMID: 30842609
Integrated analysis of relapsed B-cell precursor Acute Lymphoblastic Leukemia identifies subtype-specific cytokine and metabolic signatures.
Schroeder MP, Bastian L, Eckert C, Gökbuget N, James AR, Tanchez JO, Schlee C, Isaakidis K, Häupl B, Baum K, Migueles Lozano OA, Kouidri K, Pan KT, Urlaub H, Schwartz S, Burmeister T, von Stackelberg A, Hoelzer D, Pfeiffer H, Rieger MA, Göllner S, Oellerich T, Horstman M, Schrappe M, Wolf J, Kirschner-Schwabe R, Brüggemann M, Müller-Tidow C, Serve H, Neumann M, Baldus CD. Schroeder MP, et al. Among authors: bastian l. Sci Rep. 2019 Mar 12;9(1):4188. doi: 10.1038/s41598-019-40786-1. Sci Rep. 2019. PMID: 30862934 Free PMC article. Clinical Trial.
In vivo inducible reverse genetics in patients' tumors to identify individual therapeutic targets.
Carlet M, Völse K, Vergalli J, Becker M, Herold T, Arner A, Senft D, Jurinovic V, Liu WH, Gao Y, Dill V, Fehse B, Baldus CD, Bastian L, Lenk L, Schewe DM, Bagnoli JW, Vick B, Schmid JP, Wilhelm A, Marschalek R, Jost PJ, Miething C, Riecken K, Schmidt-Supprian M, Binder V, Jeremias I. Carlet M, et al. Among authors: bastian l. Nat Commun. 2021 Sep 27;12(1):5655. doi: 10.1038/s41467-021-25963-z. Nat Commun. 2021. PMID: 34580292 Free PMC article.
Inhibiting casein kinase 2 sensitizes acute lymphoblastic leukemia cells to venetoclax via MCL1 degradation.
Lázaro-Navarro J, Pimentel-Gutiérrez HJ, Gauert A, Hagemann AIH, Eisenschmid J, Gökbuget N, Vick B, Jeremias I, Seyfried F, Meyer LH, Debatin KM, Richer K, Bultman M, Neumann M, Hänzelmann S, Serve H, Astrahantseff K, Rieger MA, Eckert C, Baldus CD, Bastian L. Lázaro-Navarro J, et al. Among authors: bastian l. Blood Adv. 2021 Dec 28;5(24):5501-5506. doi: 10.1182/bloodadvances.2021004513. Blood Adv. 2021. PMID: 34610112 Free PMC article. No abstract available.
UBTF::ATXN7L3 gene fusion defines novel B cell precursor ALL subtype with CDX2 expression and need for intensified treatment.
Bastian L, Hartmann AM, Beder T, Hänzelmann S, Kässens J, Bultmann M, Hoeppner MP, Franzenburg S, Wittig M, Franke A, Nagel I, Spielmann M, Reimer N, Busch H, Schwartz S, Steffen B, Viardot A, Döhner K, Kondakci M, Wulf G, Wendelin K, Renzelmann A, Kiani A, Trautmann H, Neumann M, Gökbuget N, Brüggemann M, Baldus CD. Bastian L, et al. Leukemia. 2022 Jun;36(6):1676-1680. doi: 10.1038/s41375-022-01557-6. Epub 2022 Apr 9. Leukemia. 2022. PMID: 35397658 Free PMC article. No abstract available.
An alternative CYB5A transcript is expressed in aneuploid ALL and enriched in relapse.
Bartsch L, Schroeder MP, Hänzelmann S, Bastian L, Lázaro-Navarro J, Schlee C, Tanchez JO, Schulze V, Isaakidis K, Rieger MA, Gökbuget N, Eckert C, Serve H, Horstmann M, Schrappe M, Brüggemann M, Baldus CD, Neumann M. Bartsch L, et al. Among authors: bastian l. BMC Genom Data. 2022 Apr 18;23(1):30. doi: 10.1186/s12863-022-01041-1. BMC Genom Data. 2022. PMID: 35436854 Free PMC article.
Combining daratumumab with CD47 blockade prolongs survival in preclinical models of pediatric T-ALL.
Müller K, Vogiatzi F, Winterberg D, Rösner T, Lenk L, Bastian L, Gehlert CL, Autenrieb MP, Brüggemann M, Cario G, Schrappe M, Kulozik AE, Eckert C, Bergmann AK, Bornhauser B, Bourquin JP, Valerius T, Peipp M, Kellner C, Schewe DM. Müller K, et al. Among authors: bastian l. Blood. 2022 Jul 7;140(1):45-57. doi: 10.1182/blood.2021014485. Blood. 2022. PMID: 35452517 Free article.
378 results