Bastiaens PI - Search Results

1

Identification of pyrazolopyridazinones as PDEδ inhibitors.

Papke B, Murarka S, Vogel HA, Martín-Gago P, Kovacevic M, Truxius DC, Fansa EK, Ismail S, Zimmermann G, Heinelt K, Schultz-Fademrecht C, Al Saabi A, Baumann M, Nussbaumer P, Wittinghofer A, Waldmann H, Bastiaens PI. Papke B, et al. Among authors: bastiaens pi. Nat Commun. 2016 Apr 20;7:11360. doi: 10.1038/ncomms11360. Nat Commun. 2016. PMID: 27094677 Free PMC article.

2

An acylation cycle regulates localization and activity of palmitoylated Ras isoforms.

Rocks O, Peyker A, Kahms M, Verveer PJ, Koerner C, Lumbierres M, Kuhlmann J, Waldmann H, Wittinghofer A, Bastiaens PI. Rocks O, et al. Among authors: bastiaens pi. Science. 2005 Mar 18;307(5716):1746-52. doi: 10.1126/science.1105654. Epub 2005 Feb 10. Science. 2005. PMID: 15705808

3

Fluorescence fluctuations of quantum-dot sensors capture intracellular protein interaction dynamics.

Zamir E, Lommerse PH, Kinkhabwala A, Grecco HE, Bastiaens PI. Zamir E, et al. Among authors: bastiaens pi. Nat Methods. 2010 Apr;7(4):295-8. doi: 10.1038/nmeth.1441. Epub 2010 Mar 14. Nat Methods. 2010. PMID: 20228813

4

Small-molecule inhibition of APT1 affects Ras localization and signaling.

Dekker FJ, Rocks O, Vartak N, Menninger S, Hedberg C, Balamurugan R, Wetzel S, Renner S, Gerauer M, Schölermann B, Rusch M, Kramer JW, Rauh D, Coates GW, Brunsveld L, Bastiaens PI, Waldmann H. Dekker FJ, et al. Among authors: bastiaens pi. Nat Chem Biol. 2010 Jun;6(6):449-56. doi: 10.1038/nchembio.362. Epub 2010 Apr 25. Nat Chem Biol. 2010. PMID: 20418879

5

In situ analysis of tyrosine phosphorylation networks by FLIM on cell arrays.

Grecco HE, Roda-Navarro P, Girod A, Hou J, Frahm T, Truxius DC, Pepperkok R, Squire A, Bastiaens PI. Grecco HE, et al. Among authors: bastiaens pi. Nat Methods. 2010 Jun;7(6):467-72. doi: 10.1038/nmeth.1458. Epub 2010 May 9. Nat Methods. 2010. PMID: 20453867

6

Development of highly potent inhibitors of the Ras-targeting human acyl protein thioesterases based on substrate similarity design.

Hedberg C, Dekker FJ, Rusch M, Renner S, Wetzel S, Vartak N, Gerding-Reimers C, Bon RS, Bastiaens PI, Waldmann H. Hedberg C, et al. Among authors: bastiaens pi. Angew Chem Int Ed Engl. 2011 Oct 10;50(42):9832-7. doi: 10.1002/anie.201102965. Epub 2011 Sep 9. Angew Chem Int Ed Engl. 2011. PMID: 21905185

7

Arl2-GTP and Arl3-GTP regulate a GDI-like transport system for farnesylated cargo.

Ismail SA, Chen YX, Rusinova A, Chandra A, Bierbaum M, Gremer L, Triola G, Waldmann H, Bastiaens PI, Wittinghofer A. Ismail SA, et al. Among authors: bastiaens pi. Nat Chem Biol. 2011 Oct 16;7(12):942-9. doi: 10.1038/nchembio.686. Nat Chem Biol. 2011. PMID: 22002721

8

The GDI-like solubilizing factor PDEδ sustains the spatial organization and signalling of Ras family proteins.

Chandra A, Grecco HE, Pisupati V, Perera D, Cassidy L, Skoulidis F, Ismail SA, Hedberg C, Hanzal-Bayer M, Venkitaraman AR, Wittinghofer A, Bastiaens PI. Chandra A, et al. Among authors: bastiaens pi. Nat Cell Biol. 2011 Dec 18;14(2):148-58. doi: 10.1038/ncb2394. Nat Cell Biol. 2011. PMID: 22179043

9

Selective chemical imaging of static actin in live cells.

Milroy LG, Rizzo S, Calderon A, Ellinger B, Erdmann S, Mondry J, Verveer P, Bastiaens P, Waldmann H, Dehmelt L, Arndt HD. Milroy LG, et al. J Am Chem Soc. 2012 May 23;134(20):8480-6. doi: 10.1021/ja211708z. Epub 2012 May 14. J Am Chem Soc. 2012. PMID: 22475347

10

Chemical-biological exploration of the limits of the Ras de- and repalmitoylating machinery.

Görmer K, Bürger M, Kruijtzer JA, Vetter I, Vartak N, Brunsveld L, Bastiaens PI, Liskamp RM, Triola G, Waldmann H. Görmer K, et al. Among authors: bastiaens pi. Chembiochem. 2012 May 7;13(7):1017-23. doi: 10.1002/cbic.201200078. Epub 2012 Apr 5. Chembiochem. 2012. PMID: 22488913

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