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New furoxan derivatives for the treatment of ocular hypertension.
Blangetti M, Rolando B, Chegaev K, Guglielmo S, Lazzarato L, Durante M, Masini E, Almirante N, Bastia E, Impagnatiello F, Fruttero R, Gasco A. Blangetti M, et al. Among authors: bastia e. Bioorg Med Chem Lett. 2017 Feb 1;27(3):479-483. doi: 10.1016/j.bmcl.2016.12.041. Epub 2016 Dec 18. Bioorg Med Chem Lett. 2017. PMID: 28027869 Free article.
NCX 667, a Novel Nitric Oxide Donor, Lowers Intraocular Pressure in Rabbits, Dogs, and Non-Human Primates and Enhances TGFβ2-Induced Outflow in HTM/HSC Constructs.
Bastia E, Toris CB, Brambilla S, Galli C, Almirante N, Bergamini MVW, Masini E, Sgambellone S, Unser AM, Ahmed F, Torrejon KY, Navratil T, Impagnatiello F. Bastia E, et al. Invest Ophthalmol Vis Sci. 2021 Mar 1;62(3):17. doi: 10.1167/iovs.62.3.17. Invest Ophthalmol Vis Sci. 2021. PMID: 33704360 Free PMC article.
A novel nitric oxide releasing prostaglandin analog, NCX 125, reduces intraocular pressure in rabbit, dog, and primate models of glaucoma.
Borghi V, Bastia E, Guzzetta M, Chiroli V, Toris CB, Batugo MR, Carreiro ST, Chong WK, Gale DC, Kucera DJ, Jia L, Prasanna G, Ongini E, Krauss AH, Impagnatiello F. Borghi V, et al. Among authors: bastia e. J Ocul Pharmacol Ther. 2010 Apr;26(2):125-32. doi: 10.1089/jop.2009.0120. J Ocul Pharmacol Ther. 2010. PMID: 20415621
The nitric oxide donating triamcinolone acetonide NCX 434 does not increase intraocular pressure and reduces endothelin-1 induced biochemical and functional changes in the rabbit eye.
Impagnatiello F, Giambene B, Lanzi C, Pini A, Somma T, Bastia E, Ongini E, Galassi F, Masini E. Impagnatiello F, et al. Among authors: bastia e. Br J Ophthalmol. 2012 May;96(5):757-61. doi: 10.1136/bjophthalmol-2011-300404. Epub 2012 Jan 18. Br J Ophthalmol. 2012. PMID: 22257787
Nitric oxide (NO): an emerging target for the treatment of glaucoma.
Cavet ME, Vittitow JL, Impagnatiello F, Ongini E, Bastia E. Cavet ME, et al. Among authors: bastia e. Invest Ophthalmol Vis Sci. 2014 Aug 14;55(8):5005-15. doi: 10.1167/iovs.14-14515. Invest Ophthalmol Vis Sci. 2014. PMID: 25125670 Review.
Repeated Dosing with NCX1404, a Nitric Oxide-Donating Pregabalin, Re-establishes Normal Nociceptive Responses in Mice with Streptozotocin-Induced Painful Diabetic Neuropathy.
Varani K, Vincenzi F, Targa M, Ravani A, Bastia E, Storoni L, Brambilla S, Almirante N, Impagnatiello F. Varani K, et al. Among authors: bastia e. J Pharmacol Exp Ther. 2016 May;357(2):240-7. doi: 10.1124/jpet.115.230193. Epub 2016 Feb 23. J Pharmacol Exp Ther. 2016. PMID: 26907623
30 results