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Targeted deletion of the AAA-ATPase Ruvbl1 in mice disrupts ciliary integrity and causes renal disease and hydrocephalus.
Exp Mol Med. 2018 Jun 28;50(6):1-17. doi: 10.1038/s12276-018-0108-z.
Exp Mol Med. 2018.
PMID: 29959317
Free PMC article.
Functional aspects of primary cilia in signaling, cell cycle and tumorigenesis.
Basten SG, Giles RH.
Basten SG, et al.
Cilia. 2013 Apr 29;2(1):6. doi: 10.1186/2046-2530-2-6.
Cilia. 2013.
PMID: 23628112
Free PMC article.
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A role for central spindle proteins in cilia structure and function.
Smith KR, Kieserman EK, Wang PI, Basten SG, Giles RH, Marcotte EM, Wallingford JB.
Smith KR, et al. Among authors: basten sg.
Cytoskeleton (Hoboken). 2011 Feb;68(2):112-24. doi: 10.1002/cm.20498. Epub 2011 Jan 12.
Cytoskeleton (Hoboken). 2011.
PMID: 21246755
Free PMC article.
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Reduced cilia frequencies in human renal cell carcinomas versus neighboring parenchymal tissue.
Basten SG, Willekers S, Vermaat JS, Slaats GG, Voest EE, van Diest PJ, Giles RH.
Basten SG, et al.
Cilia. 2013 Jan 31;2(1):2. doi: 10.1186/2046-2530-2-2.
Cilia. 2013.
PMID: 23369289
Free PMC article.
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Mutations in LRRC50 predispose zebrafish and humans to seminomas.
Basten SG, Davis EE, Gillis AJ, van Rooijen E, Stoop H, Babala N, Logister I, Heath ZG, Jonges TN, Katsanis N, Voest EE, van Eeden FJ, Medema RH, Ketting RF, Schulte-Merker S, Looijenga LH, Giles RH.
Basten SG, et al.
PLoS Genet. 2013 Apr;9(4):e1003384. doi: 10.1371/journal.pgen.1003384. Epub 2013 Apr 11.
PLoS Genet. 2013.
PMID: 23599692
Free PMC article.
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Rare disruptive mutations in ciliary function genes contribute to testicular cancer susceptibility.
Litchfield K, Levy M, Dudakia D, Proszek P, Shipley C, Basten S, Rapley E, Bishop DT, Reid A, Huddart R, Broderick P, Castro DG, O'Connor S, Giles RH, Houlston RS, Turnbull C.
Litchfield K, et al.
Nat Commun. 2016 Dec 20;7:13840. doi: 10.1038/ncomms13840.
Nat Commun. 2016.
PMID: 27996046
Free PMC article.
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Birt-Hogg-Dube syndrome is a novel ciliopathy.
Luijten MN, Basten SG, Claessens T, Vernooij M, Scott CL, Janssen R, Easton JA, Kamps MA, Vreeburg M, Broers JL, van Geel M, Menko FH, Harbottle RP, Nookala RK, Tee AR, Land SC, Giles RH, Coull BJ, van Steensel MA.
Luijten MN, et al. Among authors: basten sg.
Hum Mol Genet. 2013 Nov 1;22(21):4383-97. doi: 10.1093/hmg/ddt288. Epub 2013 Jun 19.
Hum Mol Genet. 2013.
PMID: 23784378
Free PMC article.
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