Basso M - Search Results

1

Looking above but not beyond the genome for therapeutics in neurology and psychiatry: epigenetic proteins and RNAs find a new focus.

Basso M, Sleiman S, Ratan RR. Basso M, et al. Neurotherapeutics. 2013 Oct;10(4):551-5. doi: 10.1007/s13311-013-0225-2. Neurotherapeutics. 2013. PMID: 24092616 Free PMC article. No abstract available.

2

Transglutaminase is a therapeutic target for oxidative stress, excitotoxicity and stroke: a new epigenetic kid on the CNS block.

Basso M, Ratan RR. Basso M, et al. J Cereb Blood Flow Metab. 2013 Jun;33(6):809-18. doi: 10.1038/jcbfm.2013.53. Epub 2013 Apr 10. J Cereb Blood Flow Metab. 2013. PMID: 23571278 Free PMC article. Review.

3

Putting the 'HAT' back on survival signalling: the promises and challenges of HDAC inhibition in the treatment of neurological conditions.

Sleiman SF, Basso M, Mahishi L, Kozikowski AP, Donohoe ME, Langley B, Ratan RR. Sleiman SF, et al. Among authors: basso m. Expert Opin Investig Drugs. 2009 May;18(5):573-84. doi: 10.1517/13543780902810345. Expert Opin Investig Drugs. 2009. PMID: 19388875 Free PMC article. Review.

4

Mithramycin is a gene-selective Sp1 inhibitor that identifies a biological intersection between cancer and neurodegeneration.

Sleiman SF, Langley BC, Basso M, Berlin J, Xia L, Payappilly JB, Kharel MK, Guo H, Marsh JL, Thompson LM, Mahishi L, Ahuja P, MacLellan WR, Geschwind DH, Coppola G, Rohr J, Ratan RR. Sleiman SF, et al. Among authors: basso m. J Neurosci. 2011 May 4;31(18):6858-70. doi: 10.1523/JNEUROSCI.0710-11.2011. J Neurosci. 2011. PMID: 21543616 Free PMC article.

5

Transglutaminase inhibition protects against oxidative stress-induced neuronal death downstream of pathological ERK activation.

Basso M, Berlin J, Xia L, Sleiman SF, Ko B, Haskew-Layton R, Kim E, Antonyak MA, Cerione RA, Iismaa SE, Willis D, Cho S, Ratan RR. Basso M, et al. J Neurosci. 2012 May 9;32(19):6561-9. doi: 10.1523/JNEUROSCI.3353-11.2012. J Neurosci. 2012. PMID: 22573678 Free PMC article.

6

Histone Deacetylase Inhibitors and Mithramycin A Impact a Similar Neuroprotective Pathway at a Crossroad between Cancer and Neurodegeneration.

Sleiman SF, Berlin J, Basso M, Karuppagounder SS, Rohr J, Ratan RR. Sleiman SF, et al. Among authors: basso m. Pharmaceuticals (Basel). 2011 Aug 22;4(8):1183-1195. doi: 10.3390/ph4081183. Pharmaceuticals (Basel). 2011. PMID: 22582024 Free PMC article.

7

Hypoxia-inducible factor prolyl hydroxylases as targets for neuroprotection by "antioxidant" metal chelators: From ferroptosis to stroke.

Speer RE, Karuppagounder SS, Basso M, Sleiman SF, Kumar A, Brand D, Smirnova N, Gazaryan I, Khim SJ, Ratan RR. Speer RE, et al. Among authors: basso m. Free Radic Biol Med. 2013 Sep;62:26-36. doi: 10.1016/j.freeradbiomed.2013.01.026. Epub 2013 Jan 31. Free Radic Biol Med. 2013. PMID: 23376032 Free PMC article. Review.

8

In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation.

Karuppagounder SS, Basso M, Sleiman SF, Ma TC, Speer RE, Smirnova NA, Gazaryan IG, Ratan RR. Karuppagounder SS, et al. Among authors: basso m. J Neurosci Res. 2013 Aug;91(8):1066-75. doi: 10.1002/jnr.23204. Epub 2013 Mar 4. J Neurosci Res. 2013. PMID: 23456821 Free PMC article.

9

Antihelminthic benzimidazoles are novel HIF activators that prevent oxidative neuronal death via binding to tubulin.

Aleyasin H, Karuppagounder SS, Kumar A, Sleiman S, Basso M, Ma T, Siddiq A, Chinta SJ, Brochier C, Langley B, Haskew-Layton R, Bane SL, Riggins GJ, Gazaryan I, Starkov AA, Andersen JK, Ratan RR. Aleyasin H, et al. Among authors: basso m. Antioxid Redox Signal. 2015 Jan 10;22(2):121-34. doi: 10.1089/ars.2013.5595. Antioxid Redox Signal. 2015. PMID: 24766300 Free PMC article.

10

Hydroxamic acid-based histone deacetylase (HDAC) inhibitors can mediate neuroprotection independent of HDAC inhibition.

Sleiman SF, Olson DE, Bourassa MW, Karuppagounder SS, Zhang YL, Gale J, Wagner FF, Basso M, Coppola G, Pinto JT, Holson EB, Ratan RR. Sleiman SF, et al. Among authors: basso m. J Neurosci. 2014 Oct 22;34(43):14328-37. doi: 10.1523/JNEUROSCI.1010-14.2014. J Neurosci. 2014. PMID: 25339746 Free PMC article.

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