Basnet SK - Search Results

1

Prevalence and Associated Factors of Adolescent Obesity among Rural School Adolescents in Nepal: A Cross-Sectional Study.

Sitaula D, Dhakal A, Lageju N, Silwal A, Basnet SK, Shrestha N, Anup Bikram BC, Phoju N. Sitaula D, et al. Among authors: basnet sk. Glob Health Epidemiol Genom. 2023 Sep 29;2023:2957278. doi: 10.1155/2023/2957278. eCollection 2023. Glob Health Epidemiol Genom. 2023. PMID: 37808524 Free PMC article.

2

Discovery of N,4-Di(1H-pyrazol-4-yl)pyrimidin-2-amine-Derived CDK2 Inhibitors as Potential Anticancer Agents: Design, Synthesis, and Evaluation.

Fanta BS, Lenjisa J, Teo T, Kou L, Mekonnen L, Yang Y, Basnet SKC, Hassankhani R, Sykes MJ, Yu M, Wang S. Fanta BS, et al. Among authors: basnet skc. Molecules. 2023 Mar 25;28(7):2951. doi: 10.3390/molecules28072951. Molecules. 2023. PMID: 37049714 Free PMC article.

3

2-Anilino-4-(1-methyl-1H-pyrazol-4-yl)pyrimidine-derived CDK2 inhibitors as anticancer agents: Design, synthesis & evaluation.

Fanta BS, Mekonnen L, Basnet SKC, Teo T, Lenjisa J, Khair NZ, Kou L, Tadesse S, Sykes MJ, Yu M, Wang S. Fanta BS, et al. Among authors: basnet skc. Bioorg Med Chem. 2023 Feb 15;80:117158. doi: 10.1016/j.bmc.2023.117158. Epub 2023 Jan 11. Bioorg Med Chem. 2023. PMID: 36706608

4

Discovery of Potent Inhibitors of Cyclin-Dependent Kinases 7 and 9: Design, Synthesis, Structure-Activity Relationship Analysis and Biological Evaluation.

Chen R, Hassankhani R, Long Y, Basnet SKC, Teo T, Yang Y, Mekonnen L, Yu M, Wang S. Chen R, et al. Among authors: basnet skc. ChemMedChem. 2023 Feb 1;18(3):e202200582. doi: 10.1002/cmdc.202200582. Epub 2022 Nov 27. ChemMedChem. 2023. PMID: 36400715

5

An Orally Bioavailable and Highly Efficacious Inhibitor of CDK9/FLT3 for the Treatment of Acute Myeloid Leukemia.

Anshabo AT, Bantie L, Diab S, Lenjisa J, Kebede A, Long Y, Heinemann G, Karanjia J, Noll B, Basnet SKC, Li M, Milne R, Albrecht H, Wang S. Anshabo AT, et al. Among authors: basnet skc. Cancers (Basel). 2022 Feb 22;14(5):1113. doi: 10.3390/cancers14051113. Cancers (Basel). 2022. PMID: 35267421 Free PMC article.

6

Discovery of novel 4-azaaryl-N-phenylpyrimidin-2-amine derivatives as potent and selective FLT3 inhibitors for acute myeloid leukaemia with FLT3 mutations.

Long Y, Yu M, Ochnik AM, Karanjia JD, Basnet SK, Kebede AA, Kou L, Wang S. Long Y, et al. Among authors: basnet sk. Eur J Med Chem. 2021 Mar 5;213:113215. doi: 10.1016/j.ejmech.2021.113215. Epub 2021 Jan 22. Eur J Med Chem. 2021. PMID: 33516985

7

Synthesis and evaluation of 2'H-spiro[cyclohexane-1,3'-imidazo[1,5-a]pyridine]-1',5'-dione derivatives as Mnk inhibitors.

Abdelaziz AM, Basnet SKC, Islam S, Li M, Tadesse S, Albrecht H, Gerber C, Yu M, Wang S. Abdelaziz AM, et al. Among authors: basnet skc. Bioorg Med Chem Lett. 2019 Sep 15;29(18):2650-2654. doi: 10.1016/j.bmcl.2019.07.043. Epub 2019 Jul 23. Bioorg Med Chem Lett. 2019. PMID: 31362920

8

Discovery of CDK5 Inhibitors through Structure-Guided Approach.

Khair NZ, Lenjisa JL, Tadesse S, Kumarasiri M, Basnet SKC, Mekonnen LB, Li M, Diab S, Sykes MJ, Albrecht H, Milne R, Wang S. Khair NZ, et al. Among authors: basnet skc. ACS Med Chem Lett. 2019 Mar 20;10(5):786-791. doi: 10.1021/acsmedchemlett.9b00029. eCollection 2019 May 9. ACS Med Chem Lett. 2019. PMID: 31098000 Free PMC article.

9

Discovery of N-Phenyl-4-(1H-pyrrol-3-yl)pyrimidin-2-amine Derivatives as Potent Mnk2 Inhibitors: Design, Synthesis, SAR Analysis, and Evaluation of in vitro Anti-leukaemic Activity.

Abdelaziz AM, Diab S, Islam S, Basnet SKC, Noll B, Li P, Mekonnen LB, Lu J, Albrecht H, Milne RW, Gerber C, Yu M, Wang S. Abdelaziz AM, et al. Among authors: basnet skc. Med Chem. 2019;15(6):602-623. doi: 10.2174/1573406415666181219111511. Med Chem. 2019. PMID: 30569866

10

Dual Inhibition of Mnk2 and FLT3 for potential treatment of acute myeloid leukaemia.

Diab S, Abdelaziz AM, Li P, Teo T, Basnet SKC, Noll B, Rahaman MH, Lu J, Hou J, Yu M, Le BT, Albrecht H, Milne RW, Wang S. Diab S, et al. Among authors: basnet skc. Eur J Med Chem. 2017 Oct 20;139:762-772. doi: 10.1016/j.ejmech.2017.08.006. Epub 2017 Aug 3. Eur J Med Chem. 2017. PMID: 28863357

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