The Ebola virus VP35 protein inhibits activation of interferon regulatory factor 3.
Basler CF, Mikulasova A, Martinez-Sobrido L, Paragas J, Mühlberger E, Bray M, Klenk HD, Palese P, García-Sastre A.
Basler CF, et al.
J Virol. 2003 Jul;77(14):7945-56. doi: 10.1128/jvi.77.14.7945-7956.2003.
J Virol. 2003.
PMID: 12829834
Free PMC article.
The Ebola virus VP35 could also prevent the virus- or double-stranded RNA-mediated transcriptional activation of both the beta IFN (IFN-beta) promoter and the IFN-stimulated ISG54 promoter (C. Basler et al., Proc. Natl. Acad. Sci. USA 97:12289-12294, 2000). ...
The Ebola virus VP35 could also prevent the virus- or double-stranded RNA-mediated transcriptional activation of both the beta IFN (IFN-beta …