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841 results

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Development of an anti-BAG3 humanized antibody for treatment of pancreatic cancer.
Basile A, De Marco M, Festa M, Falco A, Iorio V, Guerriero L, Eletto D, Rea D, Arra C, Lamolinara A, Ballerini P, Damiani V, Rosati A, Sala G, Turco MC, Marzullo L, De Laurenzi V. Basile A, et al. Mol Oncol. 2019 Jun;13(6):1388-1399. doi: 10.1002/1878-0261.12492. Epub 2019 May 17. Mol Oncol. 2019. PMID: 30973679 Free PMC article.
Role of BAG3 protein in leukemia cell survival and response to therapy.
Rosati A, Basile A, Falco A, d'Avenia M, Festa M, Graziano V, De Laurenzi V, Arra C, Pascale M, Turco MC. Rosati A, et al. Among authors: basile a. Biochim Biophys Acta. 2012 Dec;1826(2):365-9. doi: 10.1016/j.bbcan.2012.06.001. Epub 2012 Jun 15. Biochim Biophys Acta. 2012. PMID: 22710027 Review.
The anti-apoptotic BAG3 protein is expressed in lung carcinomas and regulates small cell lung carcinoma (SCLC) tumor growth.
Chiappetta G, Basile A, Barbieri A, Falco A, Rosati A, Festa M, Pasquinelli R, Califano D, Palma G, Costanzo R, Barcaroli D, Capunzo M, Franco R, Rocco G, Pascale M, Turco MC, De Laurenzi V, Arra C. Chiappetta G, et al. Among authors: basile a. Oncotarget. 2014 Aug 30;5(16):6846-53. doi: 10.18632/oncotarget.2261. Oncotarget. 2014. PMID: 25149536 Free PMC article.
BAG3 promotes pancreatic ductal adenocarcinoma growth by activating stromal macrophages.
Rosati A, Basile A, D'Auria R, d'Avenia M, De Marco M, Falco A, Festa M, Guerriero L, Iorio V, Parente R, Pascale M, Marzullo L, Franco R, Arra C, Barbieri A, Rea D, Menichini G, Hahne M, Bijlsma M, Barcaroli D, Sala G, di Mola FF, di Sebastiano P, Todoric J, Antonucci L, Corvest V, Jawhari A, Firpo MA, Tuveson DA, Capunzo M, Karin M, De Laurenzi V, Turco MC. Rosati A, et al. Among authors: basile a. Nat Commun. 2015 Nov 2;6:8695. doi: 10.1038/ncomms9695. Nat Commun. 2015. PMID: 26522614 Free PMC article.
Combined effect of anti-BAG3 and anti-PD-1 treatment on macrophage infiltrate, CD8+ T cell number and tumour growth in pancreatic cancer.
Iorio V, Rosati A, D'Auria R, De Marco M, Marzullo L, Basile A, Festa M, Pascale M, Remondelli P, Capunzo M, Sala G, Damiani V, Amodio G, Di Nicola M, Lattanzio R, Turco MC, De Laurenzi V. Iorio V, et al. Among authors: basile a. Gut. 2018 Apr;67(4):780-782. doi: 10.1136/gutjnl-2017-314225. Epub 2017 Aug 11. Gut. 2018. PMID: 28801350 Free PMC article. No abstract available.
Role of BAG3 in cancer progression: A therapeutic opportunity.
De Marco M, Basile A, Iorio V, Festa M, Falco A, Ranieri B, Pascale M, Sala G, Remondelli P, Capunzo M, Firpo MA, Pezzilli R, Marzullo L, Cavallo P, De Laurenzi V, Turco MC, Rosati A. De Marco M, et al. Among authors: basile a. Semin Cell Dev Biol. 2018 Jun;78:85-92. doi: 10.1016/j.semcdb.2017.08.049. Epub 2017 Aug 31. Semin Cell Dev Biol. 2018. PMID: 28864347 Review.
BAG3 induces α-SMA expression in human fibroblasts and its over-expression correlates with poorer survival in fibrotic cancer patients.
De Marco M, Del Papa N, Reppucci F, Iorio V, Basile A, Falco A, Iaccarino R, Brongo S, De Caro F, Capunzo M, Turco MC, Rosati A, Marzullo L. De Marco M, et al. Among authors: basile a. J Cell Biochem. 2022 Jan;123(1):91-101. doi: 10.1002/jcb.30171. Epub 2021 Nov 6. J Cell Biochem. 2022. PMID: 34741483 Free PMC article.
The antiapoptotic protein BAG3 is expressed in thyroid carcinomas and modulates apoptosis mediated by tumor necrosis factor-related apoptosis-inducing ligand.
Chiappetta G, Ammirante M, Basile A, Rosati A, Festa M, Monaco M, Vuttariello E, Pasquinelli R, Arra C, Zerilli M, Todaro M, Stassi G, Pezzullo L, Gentilella A, Tosco A, Pascale M, Marzullo L, Belisario MA, Turco MC, Leone A. Chiappetta G, et al. Among authors: basile a. J Clin Endocrinol Metab. 2007 Mar;92(3):1159-63. doi: 10.1210/jc.2006-1712. Epub 2006 Dec 12. J Clin Endocrinol Metab. 2007. PMID: 17164298
Apoptosis inhibition in cancer cells: a novel molecular pathway that involves BAG3 protein.
Rosati A, Ammirante M, Gentilella A, Basile A, Festa M, Pascale M, Marzullo L, Belisario MA, Tosco A, Franceschelli S, Moltedo O, Pagliuca G, Lerose R, Turco MC. Rosati A, et al. Among authors: basile a. Int J Biochem Cell Biol. 2007;39(7-8):1337-42. doi: 10.1016/j.biocel.2007.03.007. Epub 2007 Mar 15. Int J Biochem Cell Biol. 2007. PMID: 17493862 Review.
841 results