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First GPR119 PET Imaging Ligand: Synthesis, Radiochemistry, and Preliminary Evaluations.
J Med Chem. 2023 Jul 13;66(13):9120-9129. doi: 10.1021/acs.jmedchem.3c00720. Epub 2023 Jun 14.
J Med Chem. 2023.
PMID: 37315328
Free PMC article.
[18F]KS1, a novel ascorbate-based ligand images ROS in tumor models of rodents and nonhuman primates.
Damuka N, Bashetti N, Mintz A, Bansode AH, Miller M, Krizan I, Furdui C, Bhoopal B, Gollapelli KK, Shanmukha Kumar JV, Deep G, Dugan G, Cline M, Solingapuram Sai KK.
Damuka N, et al. Among authors: bashetti n.
Biomed Pharmacother. 2022 Dec;156:113937. doi: 10.1016/j.biopha.2022.113937. Epub 2022 Oct 29.
Biomed Pharmacother. 2022.
PMID: 36411624
Free PMC article.
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One-pot synthesis of novel tert-butyl-4-substituted phenyl-1H-1,2,3-triazolo piperazine/piperidine carboxylates, potential GPR119 agonists.
Bashetti N, Shanmukha Kumar JV, Seelam NV, Prasanna B, Mintz A, Damuka N, Devanathan S, Solingapuram Sai KK.
Bashetti N, et al.
Bioorg Med Chem Lett. 2019 Dec 1;29(23):126707. doi: 10.1016/j.bmcl.2019.126707. Epub 2019 Sep 16.
Bioorg Med Chem Lett. 2019.
PMID: 31630858
Free PMC article.
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Initial biological evaluations of 18F-KS1, a novel ascorbate derivative to image oxidative stress in cancer.
Solingapuram Sai KK, Bashetti N, Chen X, Norman S, Hines JW, Meka O, Kumar JVS, Devanathan S, Deep G, Furdui CM, Mintz A.
Solingapuram Sai KK, et al. Among authors: bashetti n.
EJNMMI Res. 2019 May 17;9(1):43. doi: 10.1186/s13550-019-0513-x.
EJNMMI Res. 2019.
PMID: 31101996
Free PMC article.
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