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Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias.
de Matos Simoes R, Shirasaki R, Downey-Kopyscinski SL, Matthews GM, Barwick BG, Gupta VA, Dupéré-Richer D, Yamano S, Hu Y, Sheffer M, Dhimolea E, Dashevsky O, Gandolfi S, Ishiguro K, Meyers RM, Bryan JG, Dharia NV, Hengeveld PJ, Brüggenthies JB, Tang H, Aguirre AJ, Sievers QL, Ebert BL, Glassner BJ, Ott CJ, Bradner JE, Kwiatkowski NP, Auclair D, Levy J, Keats JJ, Groen RWJ, Gray NS, Culhane AC, McFarland JM, Dempster JM, Licht JD, Boise LH, Hahn WC, Vazquez F, Tsherniak A, Mitsiades CS. de Matos Simoes R, et al. Among authors: barwick bg. Nat Cancer. 2023 May;4(5):754-773. doi: 10.1038/s43018-023-00550-x. Epub 2023 May 26. Nat Cancer. 2023. PMID: 37237081
CD86 regulates myeloma cell survival.
Gavile CM, Barwick BG, Newman S, Neri P, Nooka AK, Lonial S, Lee KP, Boise LH. Gavile CM, et al. Among authors: barwick bg. Blood Adv. 2017 Nov 16;1(25):2307-2319. doi: 10.1182/bloodadvances.2017011601. eCollection 2017 Nov 28. Blood Adv. 2017. PMID: 29296880 Free PMC article.
Multiple myeloma immunoglobulin lambda translocations portend poor prognosis.
Barwick BG, Neri P, Bahlis NJ, Nooka AK, Dhodapkar MV, Jaye DL, Hofmeister CC, Kaufman JL, Gupta VA, Auclair D, Keats JJ, Lonial S, Vertino PM, Boise LH. Barwick BG, et al. Nat Commun. 2019 Apr 23;10(1):1911. doi: 10.1038/s41467-019-09555-6. Nat Commun. 2019. PMID: 31015454 Free PMC article.
Gain of Chromosome 1q is associated with early progression in multiple myeloma patients treated with lenalidomide, bortezomib, and dexamethasone.
Schmidt TM, Barwick BG, Joseph N, Heffner LT, Hofmeister CC, Bernal L, Dhodapkar MV, Gupta VA, Jaye DL, Wu J, Goyal S, Chen Z, Boise LH, Lonial S, Nooka AK, Kaufman JL. Schmidt TM, et al. Among authors: barwick bg. Blood Cancer J. 2019 Nov 25;9(12):94. doi: 10.1038/s41408-019-0254-0. Blood Cancer J. 2019. PMID: 31767829 Free PMC article.
59 results