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Page 1
Development of a Dihydroquinoline-Pyrazoline GluN2C/2D-Selective Negative Allosteric Modulator of the N-Methyl-d-aspartate Receptor.
D'Erasmo MP, Akins NS, Ma P, Jing Y, Swanger SA, Sharma SK, Bartsch PW, Menaldino DS, Arcoria PJ, Bui TT, Pons-Bennaceur A, Le P, Allen JP, Ullman EZ, Nocilla KA, Zhang J, Perszyk RE, Kim S, Acker TM, Taz A, Burton SL, Coe K, Fritzemeier RG, Burnashev N, Yuan H, Liotta DC, Traynelis SF. D'Erasmo MP, et al. Among authors: bartsch pw. ACS Chem Neurosci. 2023 Sep 6;14(17):3059-3076. doi: 10.1021/acschemneuro.3c00181. Epub 2023 Aug 11. ACS Chem Neurosci. 2023. PMID: 37566734 Free PMC article.
Accelerated Discovery of Potent Fusion Inhibitors for Respiratory Syncytial Virus.
Pribut N, Kaiser TM, Wilson RJ, Jecs E, Dentmon ZW, Pelly SC, Sharma S, Bartsch PW 3rd, Burger PB, Hwang SS, Le T, Sourimant J, Yoon JJ, Plemper RK, Liotta DC. Pribut N, et al. Among authors: bartsch pw 3rd. ACS Infect Dis. 2020 May 8;6(5):922-929. doi: 10.1021/acsinfecdis.9b00524. Epub 2020 Apr 20. ACS Infect Dis. 2020. PMID: 32275393 Free PMC article.
Expanding the toolbox of metabolically stable lipid prodrug strategies.
Toti KS, Pribut N, D'Erasmo M, Dasari M, Sharma SK, Bartsch PW, Burton SL, Gold HB, Bushnev A, Derdeyn CA, Basson AE, Liotta DC, Miller EJ. Toti KS, et al. Among authors: bartsch pw. Front Pharmacol. 2023 Jan 6;13:1083284. doi: 10.3389/fphar.2022.1083284. eCollection 2022. Front Pharmacol. 2023. PMID: 36686712 Free PMC article.
Discovery of 5'-Substituted 5-Fluoro-2'-deoxyuridine Monophosphate Analogs: A Novel Class of Thymidylate Synthase Inhibitors.
Dasari M, Pelly SC, Geng J, Gold HB, Pribut N, Sharma SK, D'Erasmo MP, Bartsch PW, Sun C, Toti K, Arnold RS, Petros JA, Xu L, Jiang Y, Miller EJ, Liotta DC. Dasari M, et al. Among authors: bartsch pw. ACS Pharmacol Transl Sci. 2023 Feb 23;6(5):702-709. doi: 10.1021/acsptsci.2c00252. eCollection 2023 May 12. ACS Pharmacol Transl Sci. 2023. PMID: 37200809 Free PMC article.
Design and Optimization of Novel Competitive, Non-peptidic, SARS-CoV-2 Mpro Inhibitors.
Jacobs L, van der Westhuyzen A, Pribut N, Dentmon ZW, Cui D, D'Erasmo MP, Bartsch PW, Liu K, Cox RM, Greenlund SF, Plemper RK, Mitchell D, Marlow J, Andrews MK, Krueger RE, Sticher ZM, Kolykhalov AA, Natchus MG, Zhou B, Pelly SC, Liotta DC. Jacobs L, et al. Among authors: bartsch pw. ACS Med Chem Lett. 2023 Sep 28;14(10):1434-1440. doi: 10.1021/acsmedchemlett.3c00335. eCollection 2023 Oct 12. ACS Med Chem Lett. 2023. PMID: 37849558 Free PMC article.