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Structure-activity relationships of methoctramine-related polyamines as muscular nicotinic receptor noncompetitive antagonists. 3. Effect of inserting the tetraamine backbone into a macrocyclic structure.
Bolognesi ML, Bixel MG, Marucci G, Bartolini M, Krauss M, Angeli P, Antonello A, Rosini M, Tumiatti V, Hucho F, Melchiorre C. Bolognesi ML, et al. Among authors: bartolini m. J Med Chem. 2002 Jul 18;45(15):3286-95. doi: 10.1021/jm020835f. J Med Chem. 2002. PMID: 12109912
3-(4-[[Benzyl(methyl)amino]methyl]phenyl)-6,7-dimethoxy-2H-2-chromenone (AP2238) inhibits both acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation: a dual function lead for Alzheimer's disease therapy.
Piazzi L, Rampa A, Bisi A, Gobbi S, Belluti F, Cavalli A, Bartolini M, Andrisano V, Valenti P, Recanatini M. Piazzi L, et al. Among authors: bartolini m. J Med Chem. 2003 Jun 5;46(12):2279-82. doi: 10.1021/jm0340602. J Med Chem. 2003. PMID: 12773032
Rational approach to discover multipotent anti-Alzheimer drugs.
Rosini M, Andrisano V, Bartolini M, Bolognesi ML, Hrelia P, Minarini A, Tarozzi A, Melchiorre C. Rosini M, et al. Among authors: bartolini m. J Med Chem. 2005 Jan 27;48(2):360-3. doi: 10.1021/jm049112h. J Med Chem. 2005. PMID: 15658850
375 results