Bartholomeusz C - Search Results

1

Serotonin Analogues as Inhibitors of Breast Cancer Cell Growth.

Jose J, Tavares CDJ, Ebelt ND, Lodi A, Edupuganti R, Xie X, Devkota AK, Kaoud TS, Van Den Berg CL, Anslyn EV, Tiziani S, Bartholomeusz C, Dalby KN. Jose J, et al. Among authors: bartholomeusz c. ACS Med Chem Lett. 2017 Sep 14;8(10):1072-1076. doi: 10.1021/acsmedchemlett.7b00282. eCollection 2017 Oct 12. ACS Med Chem Lett. 2017. PMID: 29057053 Free PMC article.

2

Bisphosphorylated PEA-15 sensitizes ovarian cancer cells to paclitaxel by impairing the microtubule-destabilizing effect of SCLIP.

Xie X, Bartholomeusz C, Ahmed AA, Kazansky A, Diao L, Baggerly KA, Hortobagyi GN, Ueno NT. Xie X, et al. Among authors: bartholomeusz c. Mol Cancer Ther. 2013 Jun;12(6):1099-111. doi: 10.1158/1535-7163.MCT-12-0737. Epub 2013 Mar 29. Mol Cancer Ther. 2013. PMID: 23543364 Free PMC article.

3

MEK Inhibitor Selumetinib (AZD6244; ARRY-142886) Prevents Lung Metastasis in a Triple-Negative Breast Cancer Xenograft Model.

Bartholomeusz C, Xie X, Pitner MK, Kondo K, Dadbin A, Lee J, Saso H, Smith PD, Dalby KN, Ueno NT. Bartholomeusz C, et al. Mol Cancer Ther. 2015 Dec;14(12):2773-81. doi: 10.1158/1535-7163.MCT-15-0243. Epub 2015 Sep 17. Mol Cancer Ther. 2015. PMID: 26384399 Free PMC article.

4

Antitumor Activity of KW-2450 against Triple-Negative Breast Cancer by Inhibiting Aurora A and B Kinases.

Kai K, Kondo K, Wang X, Xie X, Pitner MK, Reyes ME, Torres-Adorno AM, Masuda H, Hortobagyi GN, Bartholomeusz C, Saya H, Tripathy D, Sen S, Ueno NT. Kai K, et al. Among authors: bartholomeusz c. Mol Cancer Ther. 2015 Dec;14(12):2687-99. doi: 10.1158/1535-7163.MCT-15-0096. Epub 2015 Oct 6. Mol Cancer Ther. 2015. PMID: 26443806 Free PMC article.

5

c-Jun N-terminal kinase promotes stem cell phenotype in triple-negative breast cancer through upregulation of Notch1 via activation of c-Jun.

Xie X, Kaoud TS, Edupuganti R, Zhang T, Kogawa T, Zhao Y, Chauhan GB, Giannoukos DN, Qi Y, Tripathy D, Wang J, Gray NS, Dalby KN, Bartholomeusz C, Ueno NT. Xie X, et al. Among authors: bartholomeusz c. Oncogene. 2017 May 4;36(18):2599-2608. doi: 10.1038/onc.2016.417. Epub 2016 Dec 12. Oncogene. 2017. PMID: 27941886 Free PMC article.

6

Discovery of a potent inhibitor of MELK that inhibits expression of the anti-apoptotic protein Mcl-1 and TNBC cell growth.

Edupuganti R, Taliaferro JM, Wang Q, Xie X, Cho EJ, Vidhu F, Ren P, Anslyn EV, Bartholomeusz C, Dalby KN. Edupuganti R, et al. Among authors: bartholomeusz c. Bioorg Med Chem. 2017 May 1;25(9):2609-2616. doi: 10.1016/j.bmc.2017.03.018. Epub 2017 Mar 10. Bioorg Med Chem. 2017. PMID: 28351607

7

MELK: a potential novel therapeutic target for TNBC and other aggressive malignancies.

Pitner MK, Taliaferro JM, Dalby KN, Bartholomeusz C. Pitner MK, et al. Among authors: bartholomeusz c. Expert Opin Ther Targets. 2017 Sep;21(9):849-859. doi: 10.1080/14728222.2017.1363183. Epub 2017 Aug 16. Expert Opin Ther Targets. 2017. PMID: 28764577 Review.

8

A Novel Class of Common Docking Domain Inhibitors That Prevent ERK2 Activation and Substrate Phosphorylation.

Sammons RM, Perry NA, Li Y, Cho EJ, Piserchio A, Zamora-Olivares DP, Ghose R, Kaoud TS, Debevec G, Bartholomeusz C, Gurevich VV, Iverson TM, Giulianotti M, Houghten RA, Dalby KN. Sammons RM, et al. Among authors: bartholomeusz c. ACS Chem Biol. 2019 Jun 21;14(6):1183-1194. doi: 10.1021/acschembio.9b00093. Epub 2019 May 13. ACS Chem Biol. 2019. PMID: 31058487 Free PMC article.

9

Differential functions of ERK1 and ERK2 in lung metastasis processes in triple-negative breast cancer.

Gagliardi M, Pitner MK, Park J, Xie X, Saso H, Larson RA, Sammons RM, Chen H, Wei C, Masuda H, Chauhan G, Kondo K, Tripathy D, Ueno NT, Dalby KN, Debeb BG, Bartholomeusz C. Gagliardi M, et al. Among authors: bartholomeusz c. Sci Rep. 2020 May 22;10(1):8537. doi: 10.1038/s41598-020-65250-3. Sci Rep. 2020. PMID: 32444778 Free PMC article.

10

Birinapant Enhances Gemcitabine's Antitumor Efficacy in Triple-Negative Breast Cancer by Inducing Intrinsic Pathway-Dependent Apoptosis.

Xie X, Lee J, Liu H, Pearson T, Lu AY, Tripathy D, Devi GR, Bartholomeusz C, Ueno NT. Xie X, et al. Among authors: bartholomeusz c. Mol Cancer Ther. 2021 Feb;20(2):296-306. doi: 10.1158/1535-7163.MCT-19-1160. Epub 2020 Dec 15. Mol Cancer Ther. 2021. PMID: 33323457 Free PMC article.

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