Bartesaghi R - Search Results

1

HDAC4: a key factor underlying brain developmental alterations in CDKL5 disorder.

Trazzi S, Fuchs C, Viggiano R, De Franceschi M, Valli E, Jedynak P, Hansen FK, Perini G, Rimondini R, Kurz T, Bartesaghi R, Ciani E. Trazzi S, et al. Among authors: bartesaghi r. Hum Mol Genet. 2016 Sep 15;25(18):3887-3907. doi: 10.1093/hmg/ddw231. Epub 2016 Jul 27. Hum Mol Genet. 2016. PMID: 27466189

2

APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome.

Trazzi S, Mitrugno VM, Valli E, Fuchs C, Rizzi S, Guidi S, Perini G, Bartesaghi R, Ciani E. Trazzi S, et al. Among authors: bartesaghi r. Hum Mol Genet. 2011 Apr 15;20(8):1560-73. doi: 10.1093/hmg/ddr033. Epub 2011 Jan 25. Hum Mol Genet. 2011. PMID: 21266456

3

CDKL5, a novel MYCN-repressed gene, blocks cell cycle and promotes differentiation of neuronal cells.

Valli E, Trazzi S, Fuchs C, Erriquez D, Bartesaghi R, Perini G, Ciani E. Valli E, et al. Among authors: bartesaghi r. Biochim Biophys Acta. 2012 Nov-Dec;1819(11-12):1173-85. doi: 10.1016/j.bbagrm.2012.08.001. Epub 2012 Aug 19. Biochim Biophys Acta. 2012. PMID: 22921766 Free PMC article.

4

Loss of CDKL5 impairs survival and dendritic growth of newborn neurons by altering AKT/GSK-3β signaling.

Fuchs C, Trazzi S, Torricella R, Viggiano R, De Franceschi M, Amendola E, Gross C, Calzà L, Bartesaghi R, Ciani E. Fuchs C, et al. Among authors: bartesaghi r. Neurobiol Dis. 2014 Oct;70(100):53-68. doi: 10.1016/j.nbd.2014.06.006. Epub 2014 Jun 18. Neurobiol Dis. 2014. PMID: 24952363 Free PMC article.

5

Inhibition of GSK3β rescues hippocampal development and learning in a mouse model of CDKL5 disorder.

Fuchs C, Rimondini R, Viggiano R, Trazzi S, De Franceschi M, Bartesaghi R, Ciani E. Fuchs C, et al. Among authors: bartesaghi r. Neurobiol Dis. 2015 Oct;82:298-310. doi: 10.1016/j.nbd.2015.06.018. Epub 2015 Jul 2. Neurobiol Dis. 2015. PMID: 26143616

6

CDKL5 protein substitution therapy rescues neurological phenotypes of a mouse model of CDKL5 disorder.

Trazzi S, De Franceschi M, Fuchs C, Bastianini S, Viggiano R, Lupori L, Mazziotti R, Medici G, Lo Martire V, Ren E, Rimondini R, Zoccoli G, Bartesaghi R, Pizzorusso T, Ciani E. Trazzi S, et al. Among authors: bartesaghi r. Hum Mol Genet. 2018 May 1;27(9):1572-1592. doi: 10.1093/hmg/ddy064. Hum Mol Genet. 2018. PMID: 29474534

7

The amyloid precursor protein (APP) triplicated gene impairs neuronal precursor differentiation and neurite development through two different domains in the Ts65Dn mouse model for Down syndrome.

Trazzi S, Fuchs C, Valli E, Perini G, Bartesaghi R, Ciani E. Trazzi S, et al. Among authors: bartesaghi r. J Biol Chem. 2013 Jul 19;288(29):20817-20829. doi: 10.1074/jbc.M113.451088. Epub 2013 Jun 5. J Biol Chem. 2013. PMID: 23740250 Free PMC article. Retracted.

8

APP-dependent alteration of GSK3β activity impairs neurogenesis in the Ts65Dn mouse model of Down syndrome.

Trazzi S, Fuchs C, De Franceschi M, Mitrugno VM, Bartesaghi R, Ciani E. Trazzi S, et al. Among authors: bartesaghi r. Neurobiol Dis. 2014 Jul;67:24-36. doi: 10.1016/j.nbd.2014.03.003. Epub 2014 Mar 15. Neurobiol Dis. 2014. PMID: 24636797

9

Inhibition of APP gamma-secretase restores Sonic Hedgehog signaling and neurogenesis in the Ts65Dn mouse model of Down syndrome.

Giacomini A, Stagni F, Trazzi S, Guidi S, Emili M, Brigham E, Ciani E, Bartesaghi R. Giacomini A, et al. Among authors: bartesaghi r. Neurobiol Dis. 2015 Oct;82:385-396. doi: 10.1016/j.nbd.2015.08.001. Epub 2015 Aug 5. Neurobiol Dis. 2015. PMID: 26254735 Free PMC article.

10

Short- and long-term effects of neonatal pharmacotherapy with epigallocatechin-3-gallate on hippocampal development in the Ts65Dn mouse model of Down syndrome.

Stagni F, Giacomini A, Emili M, Trazzi S, Guidi S, Sassi M, Ciani E, Rimondini R, Bartesaghi R. Stagni F, et al. Among authors: bartesaghi r. Neuroscience. 2016 Oct 1;333:277-301. doi: 10.1016/j.neuroscience.2016.07.031. Epub 2016 Jul 25. Neuroscience. 2016. PMID: 27457036

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