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Dengue virus NS1 secretion is regulated via importin-subunit β1 controlling expression of the chaperone GRp78 and targeted by the clinical drug ivermectin.
Denolly S, Guo H, Martens M, Płaszczyca A, Scaturro P, Prasad V, Kongmanas K, Punyadee N, Songjaeng A, Mairiang D, Pichlmair A, Avirutnan P, Bartenschlager R. Denolly S, et al. Among authors: bartenschlager r. mBio. 2023 Oct 31;14(5):e0144123. doi: 10.1128/mbio.01441-23. Epub 2023 Sep 13. mBio. 2023. PMID: 37702492 Free PMC article.
Dengue Virus Perturbs Mitochondrial Morphodynamics to Dampen Innate Immune Responses.
Chatel-Chaix L, Cortese M, Romero-Brey I, Bender S, Neufeldt CJ, Fischl W, Scaturro P, Schieber N, Schwab Y, Fischer B, Ruggieri A, Bartenschlager R. Chatel-Chaix L, et al. Among authors: bartenschlager r. Cell Host Microbe. 2016 Sep 14;20(3):342-356. doi: 10.1016/j.chom.2016.07.008. Epub 2016 Aug 18. Cell Host Microbe. 2016. PMID: 27545046 Free PMC article.
An orthogonal proteomic survey uncovers novel Zika virus host factors.
Scaturro P, Stukalov A, Haas DA, Cortese M, Draganova K, Płaszczyca A, Bartenschlager R, Götz M, Pichlmair A. Scaturro P, et al. Among authors: bartenschlager r. Nature. 2018 Sep;561(7722):253-257. doi: 10.1038/s41586-018-0484-5. Epub 2018 Sep 3. Nature. 2018. PMID: 30177828
A novel interaction between dengue virus nonstructural protein 1 and the NS4A-2K-4B precursor is required for viral RNA replication but not for formation of the membranous replication organelle.
Płaszczyca A, Scaturro P, Neufeldt CJ, Cortese M, Cerikan B, Ferla S, Brancale A, Pichlmair A, Bartenschlager R. Płaszczyca A, et al. Among authors: bartenschlager r. PLoS Pathog. 2019 May 9;15(5):e1007736. doi: 10.1371/journal.ppat.1007736. eCollection 2019 May. PLoS Pathog. 2019. PMID: 31071189 Free PMC article.
437 results