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Page 1
NRF1 Is an ER Membrane Sensor that Is Central to Cholesterol Homeostasis.
Widenmaier SB, Snyder NA, Nguyen TB, Arduini A, Lee GY, Arruda AP, Saksi J, Bartelt A, Hotamisligil GS. Widenmaier SB, et al. Among authors: bartelt a. Cell. 2017 Nov 16;171(5):1094-1109.e15. doi: 10.1016/j.cell.2017.10.003. Cell. 2017. PMID: 29149604 Free article.
The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue.
Lynes MD, Leiria LO, Lundh M, Bartelt A, Shamsi F, Huang TL, Takahashi H, Hirshman MF, Schlein C, Lee A, Baer LA, May FJ, Gao F, Narain NR, Chen EY, Kiebish MA, Cypess AM, Blüher M, Goodyear LJ, Hotamisligil GS, Stanford KI, Tseng YH. Lynes MD, et al. Among authors: bartelt a. Nat Med. 2017 May;23(5):631-637. doi: 10.1038/nm.4297. Epub 2017 Mar 27. Nat Med. 2017. PMID: 28346411 Free PMC article.
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity.
Bartelt A, Widenmaier SB, Schlein C, Johann K, Goncalves RLS, Eguchi K, Fischer AW, Parlakgül G, Snyder NA, Nguyen TB, Bruns OT, Franke D, Bawendi MG, Lynes MD, Leiria LO, Tseng YH, Inouye KE, Arruda AP, Hotamisligil GS. Bartelt A, et al. Nat Med. 2018 Mar;24(3):292-303. doi: 10.1038/nm.4481. Epub 2018 Feb 5. Nat Med. 2018. PMID: 29400713 Free PMC article.
Dietary protein restriction reduces circulating VLDL triglyceride levels via CREBH-APOA5-dependent and -independent mechanisms.
Treviño-Villarreal JH, Reynolds JS, Bartelt A, Langston PK, MacArthur MR, Arduini A, Tosti V, Veronese N, Bertozzi B, Brace LE, Mejia P, Trocha K, Kajitani GS, Longchamp A, Harputlugil E, Gathungu R, Bird SS, Bullock AD, Figenshau RS, Andriole GL, Thompson A, Heeren J, Ozaki CK, Kristal BS, Fontana L, Mitchell JR. Treviño-Villarreal JH, et al. Among authors: bartelt a. JCI Insight. 2018 Nov 2;3(21):e99470. doi: 10.1172/jci.insight.99470. JCI Insight. 2018. PMID: 30385734 Free PMC article. Clinical Trial.
12-Lipoxygenase Regulates Cold Adaptation and Glucose Metabolism by Producing the Omega-3 Lipid 12-HEPE from Brown Fat.
Leiria LO, Wang CH, Lynes MD, Yang K, Shamsi F, Sato M, Sugimoto S, Chen EY, Bussberg V, Narain NR, Sansbury BE, Darcy J, Huang TL, Kodani SD, Sakaguchi M, Rocha AL, Schulz TJ, Bartelt A, Hotamisligil GS, Hirshman MF, van Leyen K, Goodyear LJ, Blüher M, Cypess AM, Kiebish MA, Spite M, Tseng YH. Leiria LO, et al. Among authors: bartelt a. Cell Metab. 2019 Oct 1;30(4):768-783.e7. doi: 10.1016/j.cmet.2019.07.001. Epub 2019 Jul 25. Cell Metab. 2019. PMID: 31353262 Free PMC article.
Proteostasis in thermogenesis and obesity.
Bartelt A, Widenmaier SB. Bartelt A, et al. Biol Chem. 2020 Aug 27;401(9):1019-1030. doi: 10.1515/hsz-2019-0427. Biol Chem. 2020. PMID: 32061163 Review.
Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport.
Bartelt A, John C, Schaltenberg N, Berbée JFP, Worthmann A, Cherradi ML, Schlein C, Piepenburg J, Boon MR, Rinninger F, Heine M, Toedter K, Niemeier A, Nilsson SK, Fischer M, Wijers SL, van Marken Lichtenbelt W, Scheja L, Rensen PCN, Heeren J. Bartelt A, et al. Nat Commun. 2017 Apr 19;8:15010. doi: 10.1038/ncomms15010. Nat Commun. 2017. PMID: 28422089 Free PMC article. Clinical Trial.
Corrigendum: The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue.
Lynes MD, Leiria LO, Lundh M, Bartelt A, Shamsi F, Huang TL, Takahashi H, Hirshman MF, Schlein C, Lee A, Baer LA, May FJ, Gao F, Narain NR, Chen EY, Kiebish MA, Cypess AM, Blüher M, Goodyear LJ, Hotamisligil GS, Stanford KI, Tseng YH. Lynes MD, et al. Among authors: bartelt a. Nat Med. 2017 Nov 7;23(11):1384. doi: 10.1038/nm1117-1384b. Nat Med. 2017. PMID: 29117173 Free PMC article.
Endogenous Fatty Acid Synthesis Drives Brown Adipose Tissue Involution.
Schlein C, Fischer AW, Sass F, Worthmann A, Tödter K, Jaeckstein MY, Behrens J, Lynes MD, Kiebish MA, Narain NR, Bussberg V, Darkwah A, Jespersen NZ, Nielsen S, Scheele C, Schweizer M, Braren I, Bartelt A, Tseng YH, Heeren J, Scheja L. Schlein C, et al. Among authors: bartelt a. Cell Rep. 2021 Jan 12;34(2):108624. doi: 10.1016/j.celrep.2020.108624. Cell Rep. 2021. PMID: 33440156 Free PMC article.
64 results