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Flavonoids increase melanin production and reduce proliferation, migration and invasion of melanoma cells by blocking endolysosomal/melanosomal TPC2.
Netcharoensirisuk P, Abrahamian C, Tang R, Chen CC, Rosato AS, Beyers W, Chao YK, Filippini A, Di Pietro S, Bartel K, Biel M, Vollmar AM, Umehara K, De-Eknamkul W, Grimm C. Netcharoensirisuk P, et al. Among authors: bartel k. Sci Rep. 2021 Apr 19;11(1):8515. doi: 10.1038/s41598-021-88196-6. Sci Rep. 2021. PMID: 33875769 Free PMC article.
Two-Pore Channel Function Is Crucial for the Migration of Invasive Cancer Cells.
Nguyen ON, Grimm C, Schneider LS, Chao YK, Atzberger C, Bartel K, Watermann A, Ulrich M, Mayr D, Wahl-Schott C, Biel M, Vollmar AM. Nguyen ON, et al. Among authors: bartel k. Cancer Res. 2017 Mar 15;77(6):1427-1438. doi: 10.1158/0008-5472.CAN-16-0852. Epub 2017 Jan 20. Cancer Res. 2017. PMID: 28108508
Selective agonist of TRPML2 reveals direct role in chemokine release from innate immune cells.
Plesch E, Chen CC, Butz E, Scotto Rosato A, Krogsaeter EK, Yinan H, Bartel K, Keller M, Robaa D, Teupser D, Holdt LM, Vollmar AM, Sippl W, Puertollano R, Medina D, Biel M, Wahl-Schott C, Bracher F, Grimm C. Plesch E, et al. Among authors: bartel k. Elife. 2018 Nov 27;7:e39720. doi: 10.7554/eLife.39720. Elife. 2018. PMID: 30479274 Free PMC article.
51 results