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A recurrent chromosomal inversion suffices for driving escape from oncogene-induced senescence via subTAD reorganization.
Zampetidis CP, Galanos P, Angelopoulou A, Zhu Y, Polyzou A, Karamitros T, Kotsinas A, Lagopati N, Mourkioti I, Mirzazadeh R, Polyzos A, Garnerone S, Mizi A, Gusmao EG, Sofiadis K, Gál Z, Larsen DH, Pefani DE, Demaria M, Tsirigos A, Crosetto N, Maya-Mendoza A, Papaspyropoulos A, Evangelou K, Bartek J, Papantonis A, Gorgoulis VG. Zampetidis CP, et al. Among authors: bartek j. Mol Cell. 2021 Dec 2;81(23):4907-4923.e8. doi: 10.1016/j.molcel.2021.10.017. Epub 2021 Nov 17. Mol Cell. 2021. PMID: 34793711 Free article.
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints.
Bartkova J, Rezaei N, Liontos M, Karakaidos P, Kletsas D, Issaeva N, Vassiliou LV, Kolettas E, Niforou K, Zoumpourlis VC, Takaoka M, Nakagawa H, Tort F, Fugger K, Johansson F, Sehested M, Andersen CL, Dyrskjot L, Ørntoft T, Lukas J, Kittas C, Helleday T, Halazonetis TD, Bartek J, Gorgoulis VG. Bartkova J, et al. Among authors: bartek j. Nature. 2006 Nov 30;444(7119):633-7. doi: 10.1038/nature05268. Nature. 2006. PMID: 17136093
Deregulated overexpression of hCdt1 and hCdc6 promotes malignant behavior.
Liontos M, Koutsami M, Sideridou M, Evangelou K, Kletsas D, Levy B, Kotsinas A, Nahum O, Zoumpourlis V, Kouloukoussa M, Lygerou Z, Taraviras S, Kittas C, Bartkova J, Papavassiliou AG, Bartek J, Halazonetis TD, Gorgoulis VG. Liontos M, et al. Among authors: bartek j. Cancer Res. 2007 Nov 15;67(22):10899-909. doi: 10.1158/0008-5472.CAN-07-2837. Cancer Res. 2007. PMID: 18006835
HCLK2 is required for activity of the DNA damage response kinase ATR.
Rendtlew Danielsen JM, Larsen DH, Schou KB, Freire R, Falck J, Bartek J, Lukas J. Rendtlew Danielsen JM, et al. Among authors: bartek j. J Biol Chem. 2009 Feb 13;284(7):4140-7. doi: 10.1074/jbc.M808174200. Epub 2008 Dec 19. J Biol Chem. 2009. PMID: 19097996 Free article.
Modulation of the E2F1-driven cancer cell fate by the DNA damage response machinery and potential novel E2F1 targets in osteosarcomas.
Liontos M, Niforou K, Velimezi G, Vougas K, Evangelou K, Apostolopoulou K, Vrtel R, Damalas A, Kontovazenitis P, Kotsinas A, Zoumpourlis V, Tsangaris GT, Kittas C, Ginsberg D, Halazonetis TD, Bartek J, Gorgoulis VG. Liontos M, et al. Among authors: bartek j. Am J Pathol. 2009 Jul;175(1):376-91. doi: 10.2353/ajpath.2009.081160. Epub 2009 Jun 18. Am J Pathol. 2009. PMID: 19541929 Free PMC article.
The chromatin-remodeling factor CHD4 coordinates signaling and repair after DNA damage.
Larsen DH, Poinsignon C, Gudjonsson T, Dinant C, Payne MR, Hari FJ, Rendtlew Danielsen JM, Menard P, Sand JC, Stucki M, Lukas C, Bartek J, Andersen JS, Lukas J. Larsen DH, et al. Among authors: bartek j. J Cell Biol. 2010 Sep 6;190(5):731-40. doi: 10.1083/jcb.200912135. Epub 2010 Aug 30. J Cell Biol. 2010. PMID: 20805324 Free PMC article.
733 results