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Synthesis and evaluation of pyrrolobenzodiazepine dimer antibody-drug conjugates with dual β-glucuronide and dipeptide triggers.
Gregson SJ, Barrett AM, Patel NV, Kang GD, Schiavone D, Sult E, Barry CS, Vijayakrishnan B, Adams LR, Masterson LA, D'Hooge F, Snaith M, Harper J, Hartley JA, Howard PW. Gregson SJ, et al. Among authors: barry cs. Eur J Med Chem. 2019 Oct 1;179:591-607. doi: 10.1016/j.ejmech.2019.06.044. Epub 2019 Jun 18. Eur J Med Chem. 2019. PMID: 31279293
Simultaneous monitoring of multiple attributes of pyrrolobenzodiazepine antibody-drug conjugates by size exclusion chromatography - high resolution mass spectrometry.
Füssl F, Barry CS, Pugh KM, Chooi KP, Vijayakrishnan B, Kang GD, von Bulow C, Howard PW, Bones J. Füssl F, et al. Among authors: barry cs. J Pharm Biomed Anal. 2021 Oct 25;205:114287. doi: 10.1016/j.jpba.2021.114287. Epub 2021 Jul 28. J Pharm Biomed Anal. 2021. PMID: 34385015 Free article.
Efficacy, Tolerability, and Pharmacokinetic Studies of Antibody-Drug Conjugates Containing a Low-Potency Pyrrolobenzodiazepine Dimer.
Gregson SJ, Pugh K, Patel N, Afif-Rider S, Vijayakrishnan B, Santos K, Riedl J, Hutchinson I, Kang GD, Chooi KP, Beard R, Adams L, Barry CS, Ball K, Masterson LA, McFarlane M, Hartley JA, Howard PW. Gregson SJ, et al. Among authors: barry cs. Mol Cancer Ther. 2022 Sep 6;21(9):1439-1448. doi: 10.1158/1535-7163.MCT-22-0145. Mol Cancer Ther. 2022. PMID: 35793464
ADCT-301, a Pyrrolobenzodiazepine (PBD) Dimer-Containing Antibody-Drug Conjugate (ADC) Targeting CD25-Expressing Hematological Malignancies.
Flynn MJ, Zammarchi F, Tyrer PC, Akarca AU, Janghra N, Britten CE, Havenith CE, Levy JN, Tiberghien A, Masterson LA, Barry C, D'Hooge F, Marafioti T, Parren PW, Williams DG, Howard PW, van Berkel PH, Hartley JA. Flynn MJ, et al. Mol Cancer Ther. 2016 Nov;15(11):2709-2721. doi: 10.1158/1535-7163.MCT-16-0233. Epub 2016 Aug 17. Mol Cancer Ther. 2016. PMID: 27535974
TR1801-ADC: a highly potent cMet antibody-drug conjugate with high activity in patient-derived xenograft models of solid tumors.
Gymnopoulos M, Betancourt O, Blot V, Fujita R, Galvan D, Lieuw V, Nguyen S, Snedden J, Stewart C, Villicana J, Wojciak J, Wong E, Pardo R, Patel N, D'Hooge F, Vijayakrishnan B, Barry C, Hartley JA, Howard PW, Newman R, Coronella J. Gymnopoulos M, et al. Mol Oncol. 2020 Jan;14(1):54-68. doi: 10.1002/1878-0261.12600. Epub 2019 Dec 3. Mol Oncol. 2020. PMID: 31736230 Free PMC article.
A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis.
MacGregor P, Gonzalez-Munoz AL, Jobe F, Taylor MC, Rust S, Sandercock AM, Macleod OJS, Van Bocxlaer K, Francisco AF, D'Hooge F, Tiberghien A, Barry CS, Howard P, Higgins MK, Vaughan TJ, Minter R, Carrington M. MacGregor P, et al. Among authors: barry cs. PLoS Negl Trop Dis. 2019 May 23;13(5):e0007373. doi: 10.1371/journal.pntd.0007373. eCollection 2019 May. PLoS Negl Trop Dis. 2019. PMID: 31120889 Free PMC article.
Schistosomiasis in Burkina Faso: review on 60 years' research.
Zida A, Guiguemde T, Sawadogo MP, Tchekounou C, Soulama I, Barry CS, Siribie M, Marks F, Sangaré I, Bamba S. Zida A, et al. Among authors: barry cs. Ann Parasitol. 2024;69(3-4). doi: 10.17420/ap6903/4.514. Ann Parasitol. 2024. PMID: 38423519 Review.
56 results