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CHO microRNA engineering is growing up: recent successes and future challenges.
Jadhav V, Hackl M, Druz A, Shridhar S, Chung CY, Heffner KM, Kreil DP, Betenbaugh M, Shiloach J, Barron N, Grillari J, Borth N. Jadhav V, et al. Among authors: barron n. Biotechnol Adv. 2013 Dec;31(8):1501-13. doi: 10.1016/j.biotechadv.2013.07.007. Epub 2013 Aug 2. Biotechnol Adv. 2013. PMID: 23916872 Free PMC article. Review.
Microarray and proteomics expression profiling identifies several candidates, including the valosin-containing protein (VCP), involved in regulating high cellular growth rate in production CHO cell lines.
Doolan P, Meleady P, Barron N, Henry M, Gallagher R, Gammell P, Melville M, Sinacore M, McCarthy K, Leonard M, Charlebois T, Clynes M. Doolan P, et al. Among authors: barron n. Biotechnol Bioeng. 2010 May 1;106(1):42-56. doi: 10.1002/bit.22670. Biotechnol Bioeng. 2010. PMID: 20091739
Predicting cell-specific productivity from CHO gene expression.
Clarke C, Doolan P, Barron N, Meleady P, O'Sullivan F, Gammell P, Melville M, Leonard M, Clynes M. Clarke C, et al. Among authors: barron n. J Biotechnol. 2011 Jan 20;151(2):159-65. doi: 10.1016/j.jbiotec.2010.11.016. Epub 2010 Nov 27. J Biotechnol. 2011. PMID: 21115077
130 results