Barrat FJ - Search Results

1

CXCL4 synergizes with TLR8 for TBK1-IRF5 activation, epigenomic remodeling and inflammatory response in human monocytes.

Yang C, Bachu M, Du Y, Brauner C, Yuan R, Ah Kioon MD, Chesi G, Barrat FJ, Ivashkiv LB. Yang C, et al. Among authors: barrat fj. Nat Commun. 2022 Jun 14;13(1):3426. doi: 10.1038/s41467-022-31132-7. Nat Commun. 2022. PMID: 35701499 Free PMC article.

2

Plasmacytoid dendritic cells promote systemic sclerosis with a key role for TLR8.

Ah Kioon MD, Tripodo C, Fernandez D, Kirou KA, Spiera RF, Crow MK, Gordon JK, Barrat FJ. Ah Kioon MD, et al. Among authors: barrat fj. Sci Transl Med. 2018 Jan 10;10(423):eaam8458. doi: 10.1126/scitranslmed.aam8458. Sci Transl Med. 2018. PMID: 29321259 Free PMC article.

3

TLR8: No gain, no pain.

Barrat FJ. Barrat FJ. J Exp Med. 2018 Dec 3;215(12):2964-2966. doi: 10.1084/jem.20181899. Epub 2018 Nov 19. J Exp Med. 2018. PMID: 30455266 Free PMC article.

4

Interferon target-gene expression and epigenomic signatures in health and disease.

Barrat FJ, Crow MK, Ivashkiv LB. Barrat FJ, et al. Nat Immunol. 2019 Dec;20(12):1574-1583. doi: 10.1038/s41590-019-0466-2. Epub 2019 Nov 19. Nat Immunol. 2019. PMID: 31745335 Free PMC article. Review.

5

Structure-Activity Relationships of Noncovalent Immunoproteasome β5i-Selective Dipeptides.

Zhan W, Singh PK, Ban Y, Qing X, Ah Kioon MD, Fan H, Zhao Q, Wang R, Sukenick G, Salmon J, Warren JD, Ma X, Barrat FJ, Nathan CF, Lin G. Zhan W, et al. Among authors: barrat fj. J Med Chem. 2020 Nov 12;63(21):13103-13123. doi: 10.1021/acs.jmedchem.0c01520. Epub 2020 Oct 23. J Med Chem. 2020. PMID: 33095579 Free PMC article.

6

Noncytotoxic Inhibition of the Immunoproteasome Regulates Human Immune Cells In Vitro and Suppresses Cutaneous Inflammation in the Mouse.

Ah Kioon MD, Pierides M, Pannellini T, Lin G, Nathan CF, Barrat FJ. Ah Kioon MD, et al. Among authors: barrat fj. J Immunol. 2021 Apr 1;206(7):1631-1641. doi: 10.4049/jimmunol.2000951. Epub 2021 Mar 5. J Immunol. 2021. PMID: 33674446 Free PMC article.

7

Chemokines form nanoparticles with DNA and can superinduce TLR-driven immune inflammation.

Du Y, Ah Kioon MD, Laurent P, Chaudhary V, Pierides M, Yang C, Oliver D, Ivashkiv LB, Barrat FJ. Du Y, et al. Among authors: barrat fj. J Exp Med. 2022 Jul 4;219(7):e20212142. doi: 10.1084/jem.20212142. Epub 2022 May 31. J Exp Med. 2022. PMID: 35640018 Free PMC article.

8

Chronic activation of pDCs in autoimmunity is linked to dysregulated ER stress and metabolic responses.

Chaudhary V, Ah Kioon MD, Hwang SM, Mishra B, Lakin K, Kirou KA, Zhang-Sun J, Wiseman RL, Spiera RF, Crow MK, Gordon JK, Cubillos-Ruiz JR, Barrat FJ. Chaudhary V, et al. Among authors: barrat fj. J Exp Med. 2022 Nov 7;219(11):e20221085. doi: 10.1084/jem.20221085. Epub 2022 Sep 2. J Exp Med. 2022. PMID: 36053251 Free PMC article.

9

Sensing of SARS-CoV-2 by pDCs and their subsequent production of IFN-I contribute to macrophage-induced cytokine storm during COVID-19.

Laurent P, Yang C, Rendeiro AF, Nilsson-Payant BE, Carrau L, Chandar V, Bram Y, tenOever BR, Elemento O, Ivashkiv LB, Schwartz RE, Barrat FJ. Laurent P, et al. Among authors: barrat fj. Sci Immunol. 2022 Sep 9;7(75):eadd4906. doi: 10.1126/sciimmunol.add4906. Epub 2022 Sep 9. Sci Immunol. 2022. PMID: 36083891 Free PMC article.

10

TLR8 escapes X chromosome inactivation in human monocytes and CD4⁺ T cells.

Youness A, Cenac C, Faz-López B, Grunenwald S, Barrat FJ, Chaumeil J, Mejía JE, Guéry JC. Youness A, et al. Among authors: barrat fj. Biol Sex Differ. 2023 Sep 18;14(1):60. doi: 10.1186/s13293-023-00544-5. Biol Sex Differ. 2023. PMID: 37723501 Free PMC article.

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