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Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade.
Pauken KE, Sammons MA, Odorizzi PM, Manne S, Godec J, Khan O, Drake AM, Chen Z, Sen DR, Kurachi M, Barnitz RA, Bartman C, Bengsch B, Huang AC, Schenkel JM, Vahedi G, Haining WN, Berger SL, Wherry EJ. Pauken KE, et al. Among authors: barnitz ra. Science. 2016 Dec 2;354(6316):1160-1165. doi: 10.1126/science.aaf2807. Epub 2016 Oct 27. Science. 2016. PMID: 27789795 Free PMC article.
The epigenetic landscape of T cell exhaustion.
Sen DR, Kaminski J, Barnitz RA, Kurachi M, Gerdemann U, Yates KB, Tsao HW, Godec J, LaFleur MW, Brown FD, Tonnerre P, Chung RT, Tully DC, Allen TM, Frahm N, Lauer GM, Wherry EJ, Yosef N, Haining WN. Sen DR, et al. Among authors: barnitz ra. Science. 2016 Dec 2;354(6316):1165-1169. doi: 10.1126/science.aae0491. Epub 2016 Oct 27. Science. 2016. PMID: 27789799 Free PMC article.
Batf-mediated epigenetic control of effector CD8+ T cell differentiation.
Tsao HW, Kaminski J, Kurachi M, Barnitz RA, DiIorio MA, LaFleur MW, Ise W, Kurosaki T, Wherry EJ, Haining WN, Yosef N. Tsao HW, et al. Among authors: barnitz ra. Sci Immunol. 2022 Feb 18;7(68):eabi4919. doi: 10.1126/sciimmunol.abi4919. Epub 2022 Feb 18. Sci Immunol. 2022. PMID: 35179948
The histone demethylase UTX regulates the lineage-specific epigenetic program of invariant natural killer T cells.
Beyaz S, Kim JH, Pinello L, Xifaras ME, Hu Y, Huang J, Kerenyi MA, Das PP, Barnitz RA, Herault A, Dogum R, Haining WN, Yilmaz ÖH, Passegue E, Yuan GC, Orkin SH, Winau F. Beyaz S, et al. Among authors: barnitz ra. Nat Immunol. 2017 Feb;18(2):184-195. doi: 10.1038/ni.3644. Epub 2016 Dec 19. Nat Immunol. 2017. PMID: 27992400 Free PMC article.
14 results