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Allelic polymorphism controls autoreactivity and vaccine elicitation of human broadly neutralizing antibodies against influenza virus.
Sangesland M, Torrents de la Peña A, Boyoglu-Barnum S, Ronsard L, Mohamed FAN, Moreno TB, Barnes RM, Rohrer D, Lonberg N, Ghebremichael M, Kanekiyo M, Ward A, Lingwood D. Sangesland M, et al. Among authors: barnes rm. Immunity. 2022 Sep 13;55(9):1693-1709.e8. doi: 10.1016/j.immuni.2022.07.006. Epub 2022 Aug 10. Immunity. 2022. PMID: 35952670 Free PMC article.
Germline-Encoded Affinity for Cognate Antigen Enables Vaccine Amplification of a Human Broadly Neutralizing Response against Influenza Virus.
Sangesland M, Ronsard L, Kazer SW, Bals J, Boyoglu-Barnum S, Yousif AS, Barnes R, Feldman J, Quirindongo-Crespo M, McTamney PM, Rohrer D, Lonberg N, Chackerian B, Graham BS, Kanekiyo M, Shalek AK, Lingwood D. Sangesland M, et al. Immunity. 2019 Oct 15;51(4):735-749.e8. doi: 10.1016/j.immuni.2019.09.001. Epub 2019 Sep 25. Immunity. 2019. PMID: 31563464 Free PMC article.
Engineering an Antibody V Gene-Selective Vaccine.
Ronsard L, Yousif AS, Peabody J, Okonkwo V, Devant P, Mogus AT, Barnes RM, Rohrer D, Lonberg N, Peabody D, Chackerian B, Lingwood D. Ronsard L, et al. Among authors: barnes rm. Front Immunol. 2021 Sep 9;12:730471. doi: 10.3389/fimmu.2021.730471. eCollection 2021. Front Immunol. 2021. PMID: 34566992 Free PMC article.
An epitope-enriched immunogen expands responses to a conserved viral site.
Caradonna TM, Ronsard L, Yousif AS, Windsor IW, Hecht R, Bracamonte-Moreno T, Roffler AA, Maron MJ, Maurer DP, Feldman J, Marchiori E, Barnes RM, Rohrer D, Lonberg N, Oguin TH 3rd, Sempowski GD, Kepler TB, Kuraoka M, Lingwood D, Schmidt AG. Caradonna TM, et al. Among authors: barnes rm. Cell Rep. 2022 Nov 8;41(6):111628. doi: 10.1016/j.celrep.2022.111628. Cell Rep. 2022. PMID: 36351401 Free PMC article.
Engaging an HIV vaccine target through the acquisition of low B cell affinity.
Ronsard L, Yousif AS, Nait Mohamed FA, Feldman J, Okonkwo V, McCarthy C, Schnabel J, Caradonna T, Barnes RM, Rohrer D, Lonberg N, Schmidt A, Lingwood D. Ronsard L, et al. Among authors: barnes rm. Nat Commun. 2023 Aug 28;14(1):5249. doi: 10.1038/s41467-023-40918-2. Nat Commun. 2023. PMID: 37640732 Free PMC article.
Humanization of a strategic CD3 epitope enables evaluation of clinical T-cell engagers in a fully immunocompetent in vivo model.
Zorn JA, Wheeler ML, Barnes RM, Kaberna J, Morishige W, Harris M, Huang RY, Lohre J, Chang YC, Chau B, Powers K, Schindler I, Neradugomma N, Thomas W, Liao X, Zhou Y, West SM, Wang F, Kotapati S, Chen G, Yamazoe S, Kosenko A, Dollinger G, Sproul T, Rajpal A, Strop P. Zorn JA, et al. Among authors: barnes rm. Sci Rep. 2022 Mar 3;12(1):3530. doi: 10.1038/s41598-022-06953-7. Sci Rep. 2022. PMID: 35241687 Free PMC article.
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