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Klebsiella pneumoniae Carbapenemase-2 (KPC-2), Substitutions at Ambler Position Asp179, and Resistance to Ceftazidime-Avibactam: Unique Antibiotic-Resistant Phenotypes Emerge from β-Lactamase Protein Engineering.
Barnes MD, Winkler ML, Taracila MA, Page MG, Desarbre E, Kreiswirth BN, Shields RK, Nguyen MH, Clancy C, Spellberg B, Papp-Wallace KM, Bonomo RA. Barnes MD, et al. mBio. 2017 Oct 31;8(5):e00528-17. doi: 10.1128/mBio.00528-17. mBio. 2017. PMID: 29089425 Free PMC article.
Probing the Mechanism of Inactivation of the FOX-4 Cephamycinase by Avibactam.
Nukaga M, Papp-Wallace KM, Hoshino T, Lefurgy ST, Bethel CR, Barnes MD, Zeiser ET, Johnson JK, Bonomo RA. Nukaga M, et al. Among authors: barnes md. Antimicrob Agents Chemother. 2018 Apr 26;62(5):e02371-17. doi: 10.1128/AAC.02371-17. Print 2018 May. Antimicrob Agents Chemother. 2018. PMID: 29439972 Free PMC article.
Relebactam Is a Potent Inhibitor of the KPC-2 β-Lactamase and Restores Imipenem Susceptibility in KPC-Producing Enterobacteriaceae.
Papp-Wallace KM, Barnes MD, Alsop J, Taracila MA, Bethel CR, Becka SA, van Duin D, Kreiswirth BN, Kaye KS, Bonomo RA. Papp-Wallace KM, et al. Among authors: barnes md. Antimicrob Agents Chemother. 2018 May 25;62(6):e00174-18. doi: 10.1128/AAC.00174-18. Print 2018 Jun. Antimicrob Agents Chemother. 2018. PMID: 29610205 Free PMC article.
Strategic Approaches to Overcome Resistance against Gram-Negative Pathogens Using β-Lactamase Inhibitors and β-Lactam Enhancers: Activity of Three Novel Diazabicyclooctanes WCK 5153, Zidebactam (WCK 5107), and WCK 4234.
Papp-Wallace KM, Nguyen NQ, Jacobs MR, Bethel CR, Barnes MD, Kumar V, Bajaksouzian S, Rudin SD, Rather PN, Bhavsar S, Ravikumar T, Deshpande PK, Patil V, Yeole R, Bhagwat SS, Patel MV, van den Akker F, Bonomo RA. Papp-Wallace KM, et al. Among authors: barnes md. J Med Chem. 2018 May 10;61(9):4067-4086. doi: 10.1021/acs.jmedchem.8b00091. Epub 2018 Apr 20. J Med Chem. 2018. PMID: 29627985 Free PMC article.
Characterization of the AmpC β-Lactamase from Burkholderia multivorans.
Becka SA, Zeiser ET, Barnes MD, Taracila MA, Nguyen K, Singh I, Sutton GG, LiPuma JJ, Fouts DE, Papp-Wallace KM. Becka SA, et al. Among authors: barnes md. Antimicrob Agents Chemother. 2018 Sep 24;62(10):e01140-18. doi: 10.1128/AAC.01140-18. Print 2018 Oct. Antimicrob Agents Chemother. 2018. PMID: 30012762 Free PMC article.
131 results