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Intracellular IRF5 Dimerization Assay.
Sherman CD, Barnes BJ. Sherman CD, et al. Among authors: barnes bj. Bio Protoc. 2021 May 20;11(10):e4021. doi: 10.21769/BioProtoc.4021. eCollection 2021 May 20. Bio Protoc. 2021. PMID: 34150928 Free PMC article.
Inhibition of IRF5 cellular activity with cell-penetrating peptides that target homodimerization.
Banga J, Srinivasan D, Sun CC, Thompson CD, Milletti F, Huang KS, Hamilton S, Song S, Hoffman AF, Qin YG, Matta B, LaPan M, Guo Q, Lu G, Li D, Qian H, Bolin DR, Liang L, Wartchow C, Qiu J, Downing M, Narula S, Fotouhi N, DeMartino JA, Tan SL, Chen G, Barnes BJ. Banga J, et al. Among authors: barnes bj. Sci Adv. 2020 May 15;6(20):eaay1057. doi: 10.1126/sciadv.aay1057. eCollection 2020 May. Sci Adv. 2020. PMID: 32440537 Free PMC article.
Inhibition of IRF5 hyperactivation protects from lupus onset and severity.
Song S, De S, Nelson V, Chopra S, LaPan M, Kampta K, Sun S, He M, Thompson CD, Li D, Shih T, Tan N, Al-Abed Y, Capitle E, Aranow C, Mackay M, Clapp WL, Barnes BJ. Song S, et al. Among authors: barnes bj. J Clin Invest. 2020 Dec 1;130(12):6700-6717. doi: 10.1172/JCI120288. J Clin Invest. 2020. PMID: 32897883 Free PMC article. Clinical Trial.
112 results