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Effects of Totum-63 on glucose homeostasis and postprandial glycemia: a translational study.
Chavanelle V, Otero YF, Le Joubioux F, Ripoche D, Bargetto M, Vluggens A, Montaurier C, Pickering G, Ducheix G, Dubray C, Dualé C, Boulliau S, Macian N, Marceau G, Sapin V, Dutheil F, Guigas B, Maugard T, Boisseau N, Cazaubiel M, Peltier SL, Sirvent P. Chavanelle V, et al. Among authors: bargetto m. Am J Physiol Endocrinol Metab. 2021 Jun 1;320(6):E1119-E1137. doi: 10.1152/ajpendo.00629.2020. Epub 2021 May 3. Am J Physiol Endocrinol Metab. 2021. PMID: 33938234 Free PMC article. Clinical Trial.
TOTUM-63, a plant-based polyphenol-rich extract, improves glycaemic control in subjects with prediabetes or early stage newly-diagnosed type 2 diabetes in a randomized, double-blind, placebo-controlled trial.
Sirvent P, Chavanelle V, Otero YF, Bargetto M, Le Joubioux F, Boisseau N, Maugard T, Cazaubiel M, Pereira B, Guigas B, Hadjadj S, Peltier SL, Marette A, Bard JM. Sirvent P, et al. Among authors: bargetto m. Diabetes Obes Metab. 2022 Dec;24(12):2331-2340. doi: 10.1111/dom.14817. Epub 2022 Aug 1. Diabetes Obes Metab. 2022. PMID: 35837981 Free PMC article. Clinical Trial.
Soluble Milk Proteins Improve Muscle Mass Recovery after Immobilization-Induced Muscle Atrophy in Old Rats but Do not Improve Muscle Functional Property Restoration.
Verney J, Martin V, Ratel S, Chavanelle V, Bargetto M, Etienne M, Chaplais E, Le Ruyet P, Bonhomme C, Combaret L, Guillet C, Boisseau N, Sirvent P, Dardevet D. Verney J, et al. Among authors: bargetto m. J Nutr Health Aging. 2017;21(10):1133-1141. doi: 10.1007/s12603-016-0855-2. J Nutr Health Aging. 2017. PMID: 29188872 Free article.
Circulating Human Metabolites Resulting from TOTUM-070 Absorption (a Plant-Based, Polyphenol-Rich Ingredient) Improve Lipid Metabolism in Human Hepatocytes: Lessons from an Original Ex Vivo Clinical Trial.
Wauquier F, Boutin-Wittrant L, Krisa S, Valls J, Langhi C, Otero YF, Sirvent P, Peltier S, Bargetto M, Cazaubiel M, Sapone V, Bouchard-Mercier A, Roux V, Macian N, Pickering G, Wittrant Y. Wauquier F, et al. Among authors: bargetto m. Nutrients. 2023 Apr 14;15(8):1903. doi: 10.3390/nu15081903. Nutrients. 2023. PMID: 37111121 Free PMC article.