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Benchmarking of T cell receptor repertoire profiling methods reveals large systematic biases.
Barennes P, Quiniou V, Shugay M, Egorov ES, Davydov AN, Chudakov DM, Uddin I, Ismail M, Oakes T, Chain B, Eugster A, Kashofer K, Rainer PP, Darko S, Ransier A, Douek DC, Klatzmann D, Mariotti-Ferrandiz E. Barennes P, et al. Nat Biotechnol. 2021 Feb;39(2):236-245. doi: 10.1038/s41587-020-0656-3. Epub 2020 Sep 7. Nat Biotechnol. 2021. PMID: 32895550 Free article.
Intrathymic adeno-associated virus gene transfer rapidly restores thymic function and long-term persistence of gene-corrected T cells.
Pouzolles M, Machado A, Guilbaud M, Irla M, Gailhac S, Barennes P, Cesana D, Calabria A, Benedicenti F, Sergé A, Raman I, Li QZ, Montini E, Klatzmann D, Adjali O, Taylor N, Zimmermann VS. Pouzolles M, et al. Among authors: barennes p. J Allergy Clin Immunol. 2020 Feb;145(2):679-697.e5. doi: 10.1016/j.jaci.2019.08.029. Epub 2019 Sep 9. J Allergy Clin Immunol. 2020. PMID: 31513879 Free PMC article.
High-resolution repertoire analysis reveals a major bystander activation of Tfh and Tfr cells.
Ritvo PG, Saadawi A, Barennes P, Quiniou V, Chaara W, El Soufi K, Bonnet B, Six A, Shugay M, Mariotti-Ferrandiz E, Klatzmann D. Ritvo PG, et al. Among authors: barennes p. Proc Natl Acad Sci U S A. 2018 Sep 18;115(38):9604-9609. doi: 10.1073/pnas.1808594115. Epub 2018 Aug 29. Proc Natl Acad Sci U S A. 2018. PMID: 30158170 Free PMC article.